Interstitial permanent implantation of ¹²⁵I seeds as salvage therapy for superficial metastatic tumor

Objective To investigate the clinical effect of ¹²⁵I seeds interstitial permanent implant for superficial metastatic tumor.

Methods Under the guidance of the B-ultrasonography, ¹²⁵I seeds were implanted into 28 units of the superficial metastatic tumor in 24 patients who had been given tumor resection, and the pain relief and tumor size were observed by means of B-ultrasonography and CT regularly after 1 month.

Results All the patients were followed-up for 1-14 months, and the median length of follow-up was 8 months. The symptoms recovered well with no adverse reaction after operation. One month after the implantation, the pain symptom was alleviated entirely in 23 lesions and partly in 5 lesions. The tumor size shrank in 25 lesions and there was no change in 3 lesions.

Conclusion Radioactive ¹²⁵I seeds interstitial permanent implantation is a simple, safe, effective method which can improve living quality of patients and ease the pain and local compression.