Hong WANG, Qiang LIU, Li-qing DU, Yan WANG, Yue FU, Feng-hua CHEN, Fei-yue FAN. Single nucleotide polymorphism of DNA repair gene hOGG1 and genetic susceptibility of cancer[J]. Int J Radiat Med Nucl Med, 2012, 36(2): 101-104. DOI: 10.3760/cma.j.issn.1673-4114.2012.02.011
Citation: Hong WANG, Qiang LIU, Li-qing DU, Yan WANG, Yue FU, Feng-hua CHEN, Fei-yue FAN. Single nucleotide polymorphism of DNA repair gene hOGG1 and genetic susceptibility of cancer[J]. Int J Radiat Med Nucl Med, 2012, 36(2): 101-104. DOI: 10.3760/cma.j.issn.1673-4114.2012.02.011
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Single nucleotide polymorphism of DNA repair gene hOGG1 and genetic susceptibility of cancer

    Abstract
  • This article discussed on the relationship between single nucleotide polymorphism of DNA repair gene human 8-oxoguanine DNA glycosylase (hOGG1) and genetic susceptibility of cancer in aspects of gene structure, biological function and relationship with disease; reviewed molecular epidemiology studies of hOGG1 and cancer genetic susceptibility; figured out the diagnosis and prevention value of hOGG1 as a biomarker of cancer susceptible populations.
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