Clinical analysis of ¹³¹I-orthoiodohippurate renogram in diagnosis of urinary system diseases

Objective To investigate the characteristics of the ¹³¹I-orthoiodohippurate renography in patients with a variety of urinary system disease.

Methods Retrospectively analyzed 190 unilateral ¹³¹I-orthoiodohippurate renography in 95 cases with urologic system disease. Disease group included the cases with unilateral or bilateral renal or ureter, bladder and prostate gland disease. The cases with normal unilateral renal or ureter were classified as normal group. The incidence of abnormal renography and the clinical featu of a variety of abnormal renography were analyzed. The SPSS.16 software was used to statistical analysis.

Results The incidence of abnormal renography in disease group was significantly higher than normal group(81.34% vs.19.64%, χ²=64.617, P < 0.005). The renographies of urethra obstruction, such as calculus and mild degree hydronephrosis, always showed steep and steadily rising curves or high flat lines. Severe hydronephrosis, renal insufficiency renographies and renal parenchymal disease showed low flat lines or straight line of low level falls gradually. The nephrograms were presenting with delayed drop of the excretory segments and stairs-like in sharp to descent in the halves or functional obstruction. Nephrogram pattern were mostly normal in the renal space-occupying lesion and adrenal glands disease. Conclusion The ¹³¹I-orthoiodohippurate renography has a higher sensitivity in assessing the hydronephrosis and renal function, it should be combined with clinical situation for lack of specificity.