Advances in application of radiotracers for glioma imaging

Nuclear medicine imaging plays an important role in diagnosis, grading and prognosis of patients with gliomas.With the development of nuclear medicine, a variety of radiotracers have been proposed used as targets for glioma imaging.At present, the most widely used SPECT radiotracers are ²⁰¹Tl, ⁹⁹Tc^m-MIBI, ¹²³I-iodo-methyl tyrosine and ¹³¹I-Buthus martensi Karsch chlorotoxin-like toxin.The most important PET radiotracers include radiolabled glucose, amino acids, choline, nucleotides and hypoxia markers.They can provide the information of substance metabolism, cell proliferation and hypoxia metabolism in gliomas to promote the accurate clinical diagnosis.This review mainly introduces the advances in application of above-mentioned radiotracers in glioma imaging.