YOU Yang, GUO Hai-zhuo, JING Shun-zi. The role of microRNA in tumor and ionizing radiation[J]. Int J Radiat Med Nucl Med, 2009, 33(4): 243-245. DOI: 10.3760/cma.j.issn.1673-4114.2009.04.016
Citation: YOU Yang, GUO Hai-zhuo, JING Shun-zi. The role of microRNA in tumor and ionizing radiation[J]. Int J Radiat Med Nucl Med, 2009, 33(4): 243-245. DOI: 10.3760/cma.j.issn.1673-4114.2009.04.016

The role of microRNA in tumor and ionizing radiation

  • MicroRNA (miRNA) are noncoding RNA of 21~25 nucleotides that act as posttranscriptional regulators of gene expression, it plays a multiple role in the regulation of cell growth and development. miRNA mutation or ectopia expression is associated with a variety of tumor. Ionizing radiation which has a carcinogenic or tumor suppressive effect induces changes in miRNA, miRNA expression changes induced by radiation are also cell-specific and gender-specific.
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