CHAI Li-ming, YANG Xiao-feng, WANG Shuang, WU Jun, ZHAO Zhou-she. Dopamine transporter imaging agent 11C-CFT and 18F-CFT and its clinical application development[J]. Int J Radiat Med Nucl Med, 2009, 33(4): 232-234. DOI: 10.3760/cma.j.issn.1673-4114.2009.04.012
Citation: CHAI Li-ming, YANG Xiao-feng, WANG Shuang, WU Jun, ZHAO Zhou-she. Dopamine transporter imaging agent 11C-CFT and 18F-CFT and its clinical application development[J]. Int J Radiat Med Nucl Med, 2009, 33(4): 232-234. DOI: 10.3760/cma.j.issn.1673-4114.2009.04.012
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Dopamine transporter imaging agent 11C-CFT and 18F-CFT and its clinical application development

    Abstract
  • 18F and 11C marked tropane derivatives is routing used PET tracer. 11C marked 11C-2β.carbomethoxy-3β-(4-fluorophenyl) tropane (11C-CFT) synthesis method is simple, have high specific activity and low cost, but 11C short half life limited the clinical application of 11C-CFT.18F-CFT was much accounted of due to long half life and easy to access.11C-CFT and 18F-CFT was both used in Paricinson disease early diagnosis and monitoring of pharmaceutical theraoy.
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