ZHA NG din-shan, DENG Yong-mei. Radiofrequency ablation and Iodine-131 labeled nuclei of tumor cells chimeric monoclonal antibody radioimmunotherapy for the treatment of lung cancer[J]. Int J Radiat Med Nucl Med, 2009, 33(3): 159-163. DOI: 10.3760/cma.j.issn.1673-4114.2009.03.008
Citation: ZHA NG din-shan, DENG Yong-mei. Radiofrequency ablation and Iodine-131 labeled nuclei of tumor cells chimeric monoclonal antibody radioimmunotherapy for the treatment of lung cancer[J]. Int J Radiat Med Nucl Med, 2009, 33(3): 159-163. DOI: 10.3760/cma.j.issn.1673-4114.2009.03.008

Radiofrequency ablation and Iodine-131 labeled nuclei of tumor cells chimeric monoclonal antibody radioimmunotherapy for the treatment of lung cancer

  • Radiofrequency ablation (RFA)is an advanced, minimally invasive technique in the treatment of patients with lung cancer and has been found to be both safe and technically feasible with a high local efficacy, but for he size of the lesion is over 3.0 cm diameter there is less effective. Iodine-131-labeled nuclei of tumor cells chimeric monoclonal antibody, a novel radioimmunotherapy provided a new therapeutic approaches for lung cancer, but the complete response is low. For RFA can induce a mass complete tumor necrosis which greatly increase the targeting area for radioimmunotherapy, thus RFA followed by 131I-nuclei of tumor cells chimeric monoclonal antibody adjuvant treatment may apparently improve the therapeutic efficacy of lung cancer, especially for tumors larger than 3.0 cm diameter.
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