Diagnostic value of serum β-human chorionic gonadotropin,progesterone and estradiol in early normal pregnancy, pregnancy abortion and ectopic pregnancy

Objective Dynamic assay of serum β-human chorionic gonadotropin(β-HCG),progesterone and estradiol value,in its analysis to identify early normal intrauterine pregnancy,abortion intrauterine pregnancy and ectopic pregnancy in value.Methods One hundred and six subject of pregnant 30~35 d of the patients were divided into three groups:early normal pregnancy group of 38 cases,early intrauterine pregnancy abortion group of 33 cases,ectopic pregnancy group of 35 cases.Determination to adopt blood β-HCG,progesterone,estradiol levels,48 h with the law after the test of the three indicators.Results β-HCG,progesterone,estradiol of normal pregnancy group were significantly higher than the pregnancy abortion group and ectopic pregnancy group.β-HCG,progesterone,estradiol of pregnancy abortion group and ectopic pregnancy group in 30~35 d was no significant difference.Retest of β-HCG,progesterone,estradiol,pregnancy abortion group progesterone decreased from(14.8±9.6)μg/L to(8.7±5.8)μg/L significantly and β-HCG,estradiol was no significant difference.To β-HCG test every 48 h increased >60%positive and progesterone=20μg/L as the threshold between the two and a joint analysis of three methods to identify normal pregnancy and abnormal pregnancy(ectopic pregnancy and pregnancy abortion),there is a better sensitivity and specificity of diagnosis.In order to test β-HCG decline >50% positive and progesterone=10μg/L as the threshold between the two and a joint analysis of three methods to identify progesterone,estradiol pregnancy abortion and ectopic pregnancy,the better sensitivity and specificity of diagnosis,analysis of both the united confirmed a higher rate.Conclusion Dynamicmonitoring of serum β-HCG, progesterone, estradiol have a certain value in early identification of the normal pregnancy, ectopic pregnancy and intrauterine pregnancy abortions.