Objective To determine the radiation quality index (QI) of the M6 CyberKnife system using the equivalent square field method.
Methods The Source-to-Chamber Distance (SCD) was set to 100 cm, with water as the measurement medium. The field size was configured as 83.2 mm×77 mm, equivalent to a 10 cm×10 cm square field. A total of 200 monitor units (MU) was delivered from the CyberKnife, and TPR
20 and TPR
10 were measured. Their ratio (TPR
20/TPR
10,
\mathrmT\mathrmP\mathrmR_10^20 
) was then calculated to obtain the QI.
Results In the Flattening Filter Free (FFF) mode, there was no significant difference between the three groups of rectangular fields of 80 mm×80 mm and 90 mm×90 mm (P>0.05). Compared with the QI value obtained via the BJR-25 method (QI2=0.667), the QI determined by the equivalent square field method (QI1=0.655) was 1.80% lower.
Conclusion Although both approaches yielded negligible differences (<0.2%) in key parameters (PU, Sw/Sa, and Kq), indicating no significant impact on dose calibration or adjustment. However, the equivalent square field method provides a more direct measurement that circumvents uncertainties associated with converting physical parameters from standard linear accelerators in the BJR-25 method. This approach is therefore more straightforward and accurate for routine calibration and quality assurance of the M6 CyberKnife system.