Research progress of neuroimaging in primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is relative rare and highly aggressive extranodal non-Hodgkin's lymphoma, accounting for 4%−6% of all extranodal lymphomas and 4% of primary central nervous system tumors. In recent years, a rising incidence has been recognized. The diagnosis of PCNSL mainly depends on stereotactic biopsy histopathological examination and surgical pathology. However, these procedures have high risks and multiple complications. Therefore, it is especially necessary to find a reliable non-invasive imaging method to evaluate PCNSL accurately. CT, MRI, PET/CT and PET/MRI are used to evaluate PCNSL currently. This review focuses on the research progress of neuroimaging in PCNSL.