Reserch progress of molecular imaging with radiolabeled nanobodies

Nanobodies have become popular targeting molecules in the field of molecular imaging due to their excellent targeting ability, superior stability, good solubility, and enhanced tissue penetration ability. A variety of nanobody-based molecular imaging probes have shown great promise for noninvasive diagnosis of human malignancies in preclinical and clinical settings. This review mainly introduces the latest research progress on nanobody-based molecular imaging probes in tumors, and further discusses the challenges and strategies for future clinical translation.