2002 Vol. 26, No. 3
Display Method:
2002, 26(3): 97-100.
[PDF 230KB]
Abstract:
Dating from the inception of percutaneous angioplasty, restenosis has been the postprocedural Achilles heel. Intravascular brachytherapy using gamma or bata radionuclides has generated tremendous excitement with promising results. The review gives update on intravascular brachytherapy, including the mechanism of radiation preventing restenosis, two basic platform for delivering endovascular radiation, the option of radianuclides,dose and dose rate, therapeutic effects, side effects and personnel exposure.
Dating from the inception of percutaneous angioplasty, restenosis has been the postprocedural Achilles heel. Intravascular brachytherapy using gamma or bata radionuclides has generated tremendous excitement with promising results. The review gives update on intravascular brachytherapy, including the mechanism of radiation preventing restenosis, two basic platform for delivering endovascular radiation, the option of radianuclides,dose and dose rate, therapeutic effects, side effects and personnel exposure.
2002, 26(3): 101-104.
Abstract:
There are total 20 years for radioactive seed implantation treatment for prostate carcinoma, especiately recent 5 years. Ultrosound or CT guidance plus computer treatment planning system make the seed implantation become more effective, minidamage and low risk of complications, it become more and more popular in clinical treatment for cancer patients.
There are total 20 years for radioactive seed implantation treatment for prostate carcinoma, especiately recent 5 years. Ultrosound or CT guidance plus computer treatment planning system make the seed implantation become more effective, minidamage and low risk of complications, it become more and more popular in clinical treatment for cancer patients.
2002, 26(3): 105-108118.
Abstract:
DIntratumoral injection of radionuclide is a new method of internal radiotherapy that has been stressed in the fields of basic research and clinical practice. It can selectively kill regional tumor while decrease radiation injury of hu-man body. But in the sides of how to select a suitable carrier, to monitor radiation dose and to determine treatment plan, we have not established a dependable system.
DIntratumoral injection of radionuclide is a new method of internal radiotherapy that has been stressed in the fields of basic research and clinical practice. It can selectively kill regional tumor while decrease radiation injury of hu-man body. But in the sides of how to select a suitable carrier, to monitor radiation dose and to determine treatment plan, we have not established a dependable system.
2002, 26(3): 109-111.
Abstract:
Renovascular hypertension (RVH) is a low prevalence and curable disease. There was a accurate results of RVH diagnosed by the tests with high sensitivity and specificity. It was known that RVH can be diagnosed and evaluated by the tests in the area of nuclear medicine. The tests in nuclear medicine is routinely the tests which diagnosed RVH before renal artery angiography.
Renovascular hypertension (RVH) is a low prevalence and curable disease. There was a accurate results of RVH diagnosed by the tests with high sensitivity and specificity. It was known that RVH can be diagnosed and evaluated by the tests in the area of nuclear medicine. The tests in nuclear medicine is routinely the tests which diagnosed RVH before renal artery angiography.
2002, 26(3): 112-114.
Abstract:
Radionuclide bone image is sensitive enough not only to diagnose jaw neoplasms,but also to estimate bone extent in jaw neoplasms. It may offer specific guidelines in determining the tumor staging and the appropriate extent of bone resection to bring down the recurrence with the increase of survival rate.
Radionuclide bone image is sensitive enough not only to diagnose jaw neoplasms,but also to estimate bone extent in jaw neoplasms. It may offer specific guidelines in determining the tumor staging and the appropriate extent of bone resection to bring down the recurrence with the increase of survival rate.
2002, 26(3): 114-118.
Abstract:
As a metabolic imaging agent,18F-fluoro-2-deoxy-D-glucose with PET imaging can reflect the function of the cell of normal tissue and carcinoma.It exerts an important role in diagnosing lung masses,differentiating the stage of lung cancer,monitoring response to treatment and assessing for recurrence and prognosis of tumor.It also can provide useful information of the grade and proliferation of lung cancer cell.With respect of the shortcoming of its resolution,18F-FDG PET should be combined with the examinations of morphology for lesion's localization.
As a metabolic imaging agent,18F-fluoro-2-deoxy-D-glucose with PET imaging can reflect the function of the cell of normal tissue and carcinoma.It exerts an important role in diagnosing lung masses,differentiating the stage of lung cancer,monitoring response to treatment and assessing for recurrence and prognosis of tumor.It also can provide useful information of the grade and proliferation of lung cancer cell.With respect of the shortcoming of its resolution,18F-FDG PET should be combined with the examinations of morphology for lesion's localization.
2002, 26(3): 124-126.
Abstract:
Most chemical carcinogens,after intake,or after metabolic activation,can form covalent modifications of DNA(DNA adducts).DNA adducts formation induced by carcinogenic chemicals reflects exposure and is directly related to tumor formation.DNA adduct is a valid indicator of early key stage of carcinogenesis.Accelarator mass spectrometry (AMS) is a relatively new nuclear technique,has been developed for the detection of DNA adduct with great detection sensitivity.This powerful application allows studying molecular effects at the low-dose carcinogen exposure.
Most chemical carcinogens,after intake,or after metabolic activation,can form covalent modifications of DNA(DNA adducts).DNA adducts formation induced by carcinogenic chemicals reflects exposure and is directly related to tumor formation.DNA adduct is a valid indicator of early key stage of carcinogenesis.Accelarator mass spectrometry (AMS) is a relatively new nuclear technique,has been developed for the detection of DNA adduct with great detection sensitivity.This powerful application allows studying molecular effects at the low-dose carcinogen exposure.
2002, 26(3): 127-130.
Abstract:
Low dose radiation (LDR) can induce adaptive response in vivo and cultured cells.This phenomenon has been confirmed for more than 10 years. After the discovery, numerous research works on its intrinsic mechanism have been carried out. It was reported that the adaptive response is related to many factors. These factors include the DNA repair system induced by LDR,the function of genes and proteins induced by LDR,the function of antioxidant enzyme,cel-luar signal transduction and cell-cycle delay relation to p53 and so on.
Low dose radiation (LDR) can induce adaptive response in vivo and cultured cells.This phenomenon has been confirmed for more than 10 years. After the discovery, numerous research works on its intrinsic mechanism have been carried out. It was reported that the adaptive response is related to many factors. These factors include the DNA repair system induced by LDR,the function of genes and proteins induced by LDR,the function of antioxidant enzyme,cel-luar signal transduction and cell-cycle delay relation to p53 and so on.
2002, 26(3): 130-133.
Abstract:
Recent preclinical and clinical research indicate that irradiation using ionizing radiation in the dose range of 15~30 Gy may reduce the occurrence of restenosis in patients who have undergone an angioplasty. Several dose point-kernel computational methods have been developed to estimate dose distribution of coronary vascular and peripheral tis-sue,The review present importance dose point-kernel in the iterafure in late year.
Recent preclinical and clinical research indicate that irradiation using ionizing radiation in the dose range of 15~30 Gy may reduce the occurrence of restenosis in patients who have undergone an angioplasty. Several dose point-kernel computational methods have been developed to estimate dose distribution of coronary vascular and peripheral tis-sue,The review present importance dose point-kernel in the iterafure in late year.
2002, 26(3): 134-136.
Abstract:
In the palliative methods of liver malignancy treatment,using 90Y-microspheres therapy can deliver the tu-moricidal dose to the tumor whilst sparing the normal tissue,so It has been used widely in clinics.This article will summarize the liver malignancy treatment methods with 90Y-microspheres and the relative dose calculating methods.
In the palliative methods of liver malignancy treatment,using 90Y-microspheres therapy can deliver the tu-moricidal dose to the tumor whilst sparing the normal tissue,so It has been used widely in clinics.This article will summarize the liver malignancy treatment methods with 90Y-microspheres and the relative dose calculating methods.
2002, 26(3): 137-140.
Abstract:
Today people pay close attention to radiation-induced second primary tumors. The type, latent period, mechanism of radiation-induced second primary tumors, familial cancer syndromes and other factors that can affect radiation-induced second primary tumors are discussed in this paper.
Today people pay close attention to radiation-induced second primary tumors. The type, latent period, mechanism of radiation-induced second primary tumors, familial cancer syndromes and other factors that can affect radiation-induced second primary tumors are discussed in this paper.
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