心肌损伤标志物的应用及临床意义

陈冀莹

Cardiac markers are presently a hot topic of studying. They now have a major role for diagnosis myocardial damage and acute myocardial infarction. It is important to search and screen a sensitive, specific and early markers of myocardial damage. The quick, accurate and sensitive assay methodology is still an important research in this field. Therefore rapid muli-analyte point-of-care tests have facilitated the use of cardiac markers for clinical management and guidance of therapy.

The application and clinical value of markers of myocardial damage

Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China

Received Date: 2004-03-22

Abstract: Cardiac markers are presently a hot topic of studying. They now have a major role for diagnosis myocardial damage and acute myocardial infarction. It is important to search and screen a sensitive, specific and early markers of myocardial damage. The quick, accurate and sensitive assay methodology is still an important research in this field. Therefore rapid muli-analyte point-of-care tests have facilitated the use of cardiac markers for clinical management and guidance of therapy.

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Reference (16)

[1]	Azzazy HME,Christenson RH.Cardiac markers of acute coronary syndromes:is there a case for point-of-care testing)[J].Clin Biochem,2002,35(1):13-27.
[2]	Alpert JS,Thygesen K,Antman E,et al.Myocardial infarction rede-fineda consensus document of The Joint European Society of Cardiology/Am College of Cardiology Committee for the redefinition of myocardial infarction[J].J Am Coll Cardiol,2000,36:959-969.
[3]	Davis GK.Role of cardiac troponin testing in percutaneous transluminal coronary angioplasty[J]. Scand J Clin Lab Invest,2003,63(3):167-174.
[4]	Nakata T,Hashimoto A,Hase M,et al.Human heart-type fatty acid-binding protein as an early diagnostic and prognostic marker in acute coronary syndrome[J].Cardiology,2003,99:96-104.
[5]	Okamoto F,Sohmiya K,Ohkaru Y,et al.Human heart-type cytoplasmic fatty acid-binding protein (H-FABP) for the diagnosis of acute myocardiac infarction.Clinical evaluation of H-FABP in comparison with myoglobin and creatine kinase isoenzyme MB[J].Clin Chem Lab Med,2000,38:231-238.
[6]	Maisel A.B-type natriuretic peptide in the diagnosis and manage-meng of congestive heart failure[J].Cardiol Clin,2001,19(4):557-571.
[7]	Dao Q,Krishnaswamy P,Kazanegra R,et al.Vtility of B type natriuretic peptide in the diagnosis of congestive heart failure in an ur-gentcare setting[J].J Am Coll Cardiol,2001,37:379-385.
[8]	James SK,Lindah B,Siegbahn A,et al.N-terminal probrain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary disease[J].Circulation,2003,108:275-281.
[9]	Venugopal J.Cardiac natriuretic peptides-hope or hype?[J]. Clin Pharm Ther,2001,26(1):15-31.
[10]	Rafav N,Ridker PM.High-sensitivity C-reative protein:a novel and promising marker of coronary heart disease[J].Clin Chem,2001,47(3):403-411.
[11]	Hainaut C,Gade W.The emerging roles of BNP and accelerated cartiac protoco in emergency laboratory medicine[J].Clin Lab Sci,2003,16(3):166-178.
[12]	Christenson RH,Duh SH,Apple FS,et al.Standardization of cardiac tropinin I assays:round robin of ten candidate reference materials[J].Clin Chem,2001,47(3):431-437.
[13]	Zaninotto M,Pagani F,Altinier S,et al.Multicenter evaluation of five assays for myoglobin determination[J]. Clin Chem,2000,46(10):1631-1637.
[14]	Collinson PO,Boa FG,Gaze DC.Measurement of cardiac tropinins[J].Ann Clin Biochem,2001,38:423-449.
[15]	Stiegler H,Fisher Y,Vazquez-Jimenez JF,et al.Lower cardiac troponin T and I results in heparin-plasma than in serum[J].Clin Chem,2000,46(9):1338-1349.
[16]	Panteghini M,Gerhardt W,Apple FS,et al.Quality specifications for cardiac troponin assays[J].Clin Chem Lab Med,2001,39(2):174-178.

The application and clinical value of markers of myocardial damage

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