Volume 25 Issue 1
Feb.  2001
Article Contents

Citation:

  • Received Date: 2000-11-10
  • Previous studies have shown that positron emission tomography (PET) can measure the biochemistry and physiologic function change in pituitary, including blood flow, perfusion, glucose metabolism, protein metabolism, receptor density. This article reviews recently research of PET imaging in pituitary adenomas. It re-flects the diagnosis, therapy management and prognosis of pituitary adenomas can be demonstrated by PET with different positron tracers. Therefore, PET imaging can lead to the improvement in research of pituitary adenomas and neurology.
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  • [1] Bergstrom M,Muhr C,Lundberg PO,et al. PET as a tool in the clinical evaluation of pituitary adenomas[J].J Nucl Med,1991,32:4610-4615.
    [2] Brunette A,Fulham MJ,Aloj L,et al. Decreased brain glucose utilization in patients with Cushing's dis-ease[J]. J Nucl Med,1998,39(5):786-790.
    [3] Meyer JH,Kennedy S,Brown GM. No effect of de-pression on [15O] H2O PET response to intravenous d-fenfluramine[J]. Am J Psychiatry,1998,155(9):1241-1246.
    [4] Daemen BJ,Zwertbroek R,Elsinga PH,et al.PET studies with L-[1-11C] tyrosine,L-[methyl-11C] methion-ine and 18F-fluorodeoxyglucose in prolactinomas in rela-tion to bromocryptine treatment[J]. Eur J Nucl Med,1991,18(7):453-460.
    [5] Lucignani G,Losa M,Moresco RM,et al. Differentia-tion of clinically non-functioning pituitary adenomas from meningiomas and craniopharyngiomas by positron emission tomography with [18 F] fluoro-ethyl-spiperone[J]. Eur J Nucl Med,1997,24(9):1149-1155.
    [6] Stolz B,Smith JPM,Albert R,et al. Biologicalcharac-terisation of [67Ga] or [68Ga] labelled DFO-octreotide(SDZ 216-927) for PET studies of somatostatin recep-tor positive tumors[J]. Horm Metab Res,1994,26(10):453-459.
    [7] Hara T,Kosaka N,Shinoura N,et al. PET imaging of brain tumor with [methyl-11C] choline[J]. J Nucl Med,1997,38(6):842-847.
    [8] Wgng GJ,Volkow ND,Fowler JS,et al. Comparison of two PET radioligands for imaging extrastriatal dopamine receptors in the human brain[J]. Synapse,1993,15(3):246-249.
    [9] De Herder W,Lamberts S. Imaging of pituitary tu-mours[J]. Baillieres Clin Endocrinol Metab,1995,9(2):367-389.
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Abstract: Previous studies have shown that positron emission tomography (PET) can measure the biochemistry and physiologic function change in pituitary, including blood flow, perfusion, glucose metabolism, protein metabolism, receptor density. This article reviews recently research of PET imaging in pituitary adenomas. It re-flects the diagnosis, therapy management and prognosis of pituitary adenomas can be demonstrated by PET with different positron tracers. Therefore, PET imaging can lead to the improvement in research of pituitary adenomas and neurology.

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