射线对血管平滑肌细胞抑制作用的机制

庄永志; 王俊杰

Endovascular radiation is a promising technique to substantianlly reduce the restenosis post-PTCA. Inhi-bition of VSMCs by radiation is thought as the main cause, but the machanism of this is not clear. Inhibition of VSMCs proliferation and miagration by radiation is ragarded as the most important factor. The role of apoptosis in this couse is not determined. However, inhibition of macrophage and cytokines by radiation is emphasized recently.

Mechanisms of radiation for the inhibition of vascular smooth musele cells

Department of Oncology, the Third Hospital of Beijing University, Beijing 100083, China

Received Date: 2000-12-14

Abstract: Endovascular radiation is a promising technique to substantianlly reduce the restenosis post-PTCA. Inhi-bition of VSMCs by radiation is thought as the main cause, but the machanism of this is not clear. Inhibition of VSMCs proliferation and miagration by radiation is ragarded as the most important factor. The role of apoptosis in this couse is not determined. However, inhibition of macrophage and cytokines by radiation is emphasized recently.

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Reference (16)

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Mechanisms of radiation for the inhibition of vascular smooth musele cells

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