Volume 26 Issue 3
Jun.  2002
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Citation:

The methods of dose estimation about the treatment with 90Y-microspheres in liver malignancy

  • Received Date: 2001-08-16
  • In the palliative methods of liver malignancy treatment,using 90Y-microspheres therapy can deliver the tu-moricidal dose to the tumor whilst sparing the normal tissue,so It has been used widely in clinics.This article will summarize the liver malignancy treatment methods with 90Y-microspheres and the relative dose calculating methods.
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    [4] HOS,Lau WY,Leung TWT. Internal radiation therapy for patients with primary or metastatic hepatic cancer[J].Cancer,1998,(9):1894-1907.
    [5] HOS,Lau WY,Leung TWT. Clinical evaluation of partition model for estimating radiation doses from yttrium-90 microspheres in the treatment of hepatic cancer[J].European Journal of Nuclear Medicine,1997.293-298.
    [6] Andrews JC,Walker SC,Ackermann RJ. Hepatic radioembolization with yttrium-90 containing glass microspheres:primary results and clinical follow-up[J].Journal of Nuclear Medicine,1994.1637-1644.
    [7] Lau WY,Ho S,Leung TWT. Selective internal radia tion therapy for nonresectable hepatocellular carcinoma with intraarterial infusion of 90Y microspheres[J].International Journal of Radiation Oncology,Biology,Physics,1998,(40):583-592.
    [8] Lin WY,Tsai SC,Hsieh JF. Effects of 90Y-microspheres on liver tumors:comparison of intratumoral injection methods and intra-arterial injection method[J].Journal of Nuclear Medicine,2000.1892-1897.
    [9] HOS,Lau WY,Leung TWT. Tumour-to-normal uptake ratio of 90Y microspheres in hepatic cancer assessed with ~(99)Tc~m macroaggregated albumin[J].British Journal of Radiology,1997,(70):823-828.
    [10] HOS,Lau WY,Leung TWT. Partition model for estimating doses from yttrium-90 microspheres in treating hepatic tumours[J].EUROPEAN JOURNAL OF NUCLEAR MEDICINE,1996.947-952.
    [11] Campbell AM,Bailey IH,Burton MA. Analysis of distribution of intra-arterial micro-spheres in human liver following hepatic yttrium-90 microspheres therapy[J].Physics in Medicine and Biology,2000,(4):1023-1033.
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    [13] Tian JH,Xu BX,Zhang JM. Ultrasound-guided internal radiotherapy using yttrium-90-glass microspheres for liver malignancies[J].Journal of Nuclear Medicine,1996.958-963.
    [14] HOS,Lau WY,Leung TWT. Comments on Ultrasound guided internal radiotherapy using yttrium-90 glass microspheres for liver malignancies[J].Journal of Nuclear Medicine,1997.1169.
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The methods of dose estimation about the treatment with 90Y-microspheres in liver malignancy

  • The Institute of Radiation Medicine, Chinese Academy of Medical Science, Peking Union Medical College, Tianjin 300192, China

Abstract: In the palliative methods of liver malignancy treatment,using 90Y-microspheres therapy can deliver the tu-moricidal dose to the tumor whilst sparing the normal tissue,so It has been used widely in clinics.This article will summarize the liver malignancy treatment methods with 90Y-microspheres and the relative dose calculating methods.

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