乳腺癌的基因治疗与核素靶向治疗

宋进华

乳腺癌的基因治疗与核素靶向治疗

宋进华

文章导航 > 国际放射医学核医学杂志 > 2003, 27 > 6: (241-244)

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乳腺癌的基因治疗与核素靶向治疗

宋进华

210009 南京, 东南大学医学院

作者简介: 宋进华(1976-),男,住院医师,硕士研究生,主要从事核素治疗的研究。;

基金项目:
国家自然科学基金资助项目(30070229)
中图分类号: R817.5

Gene therapy and radionuclides targeting therapy in mammary carcinoma

SONG Jin-hua

Department of Nuclear Medical Technique, Southeast University, Nanjing 210009, China
CLC number: R817.5

摘要: 乳腺癌的基因治疗是近年来肿瘤治疗研究的热点,目前处于实验或临床初步应用的基因治疗方法主要有免疫基因治疗、多药耐药基因治疗、反义寡核苷酸治疗、自杀基因治疗等方法,而将基因治疗与射核素相结合的基因靶向近距离放射治疗的方法具有放射性核素与自杀基因对肿瘤细胞的双重杀灭作用,为肿瘤基因治疗开辟了一条崭新的途径,在这一领域进一步研究必将加快基因靶向治疗向临床应用迈进的步伐。
- 基因治疗 /
- 靶向治疗 /
- 乳腺癌
Abstract: Breast carcinorma's gene therapy is a hotspot in study of the tumor's therapy in the recent years. Currently the major therapy methods that in the experimentative and primary clinical application phases include immunological gene therapy, multidrug rssistrance gene therapy, antisense oligonucleotide therapy and suicide gene therapy. The gene targeting brachytherapy, which is combined with gene therapy and radiotherapy has enhanced the killer effects of the suicide gene and nuclide in tumor cells. That has break a new path in tumor's gene therapy. The further study in this field will step up it's space to the clinical application.
- gene therapy /
- targeting therapy /
- mammary carcinoma
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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乳腺癌的基因治疗与核素靶向治疗

宋进华

作者简介:宋进华(1976-),男,住院医师,硕士研究生,主要从事核素治疗的研究。

210009 南京, 东南大学医学院

收稿日期: 2003-05-06

基金项目: 国家自然科学基金资助项目(30070229)

关键词:

摘要: 乳腺癌的基因治疗是近年来肿瘤治疗研究的热点,目前处于实验或临床初步应用的基因治疗方法主要有免疫基因治疗、多药耐药基因治疗、反义寡核苷酸治疗、自杀基因治疗等方法,而将基因治疗与射核素相结合的基因靶向近距离放射治疗的方法具有放射性核素与自杀基因对肿瘤细胞的双重杀灭作用,为肿瘤基因治疗开辟了一条崭新的途径,在这一领域进一步研究必将加快基因靶向治疗向临床应用迈进的步伐。