造血干细胞“归巢”机制的探讨

姜福全

造血干细胞“归巢”机制的探讨

姜福全

文章导航 > 国际放射医学核医学杂志 > 2000, 24 > 5: (234-236)

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造血干细胞“归巢”机制的探讨

姜福全

200043 上海, 第二军医大学放射医学教研室

作者简介: 姜福全(1978-),男,山东烟台人,第二军医大学硕士研究生。;

基金项目:
国家自然科学基金项目(39770329)
中图分类号: R331.2

Mechanism of hematopoietic stem cell homing

Jiang Fu-quan

Dep artment of Radiomediology, the Second Military Medical University, Shanghai, 200433, China
CLC number: R331.2

摘要: 近年来,诸如骨髓、外周血、脐血等多种来源的造血干细胞(HSC)移植在临床上日益广泛地开展起来,同时关于干细胞归巢机制的研究也有所进展。造血干细胞的归巢是一个多步骤过程。经研究发现,在归巢中涉及了干细胞表面和造血微环境中的一系列的分子与细胞因子。本文综述了其中一些研究较多的分子与因子,并对今后的研究提出了自己的看法。
- 造血干细胞 /
- 归巢
Abstract: The clinical transplantation of hematopoietic stem cell(HSC) originating from many sources such as bone marrow, peripheral blood and cord blood has been widely applied in recent years. At the same time, the development of the study on the mechanism of HSC homing which involves multi-procedures has been achieved. And a lot of molecular and cytokines on the surface or in the microenviroment of HSC are functioning in homing. The purpose of this article is to review those molecular and cytokines on which more studies have been focused in the past
- hematopoietic stem cell /
- homing
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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造血干细胞“归巢”机制的探讨

姜福全

作者简介:姜福全(1978-),男,山东烟台人,第二军医大学硕士研究生。

200043 上海, 第二军医大学放射医学教研室

收稿日期: 2000-04-06

基金项目: 国家自然科学基金项目(39770329)

关键词:

造血干细胞 /
归巢

摘要: 近年来,诸如骨髓、外周血、脐血等多种来源的造血干细胞(HSC)移植在临床上日益广泛地开展起来,同时关于干细胞归巢机制的研究也有所进展。造血干细胞的归巢是一个多步骤过程。经研究发现,在归巢中涉及了干细胞表面和造血微环境中的一系列的分子与细胞因子。本文综述了其中一些研究较多的分子与因子,并对今后的研究提出了自己的看法。