甲状腺球蛋白与分化型甲状腺癌
Thyroglobulin and differentiated thyroid cancer
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摘要: 甲状腺球蛋白(Tg)检测对分化型甲状腺癌(DTC)的诊治具有重要价值,尽管其测量受诸多因素影响,但手术及131I清除残留甲状腺后,Tg仍是监测DTC复发或转移的一项灵敏而又特异的肿瘤标志物.Tg检测与131I扫描的价值互为补充.此外,Tg免疫组化分析、Tg mRNA及Tg抗体等在DTC的诊治与随访中也具有一定价值.Abstract: Thyroglobulin(Tg) measurements play an important role in the management of differentiated thyroid carcinoma(DTC).Tg is a highly specific and sensitive tumor marker for detection of recurrence and metastasis of DTC.Tg assays and radioiodine scans are complementary.Immunohistochemical detection of Tg,Tg mRNA and thyroglobulin antibody(TgAb) also play important roles in the management of DTC.