CT和MR肝脏灌注成像技术及其临床应用

顾爱华

CT和MR肝脏灌注成像技术及其临床应用

顾爱华

文章导航 > 国际放射医学核医学杂志 > 2006, 30 > 3: (188-192)

引用本文:

Citation:

CT和MR肝脏灌注成像技术及其临床应用

顾爱华

200025 上海, 上海同济大学附属上海市第十人民医院放射科
中图分类号: R445.2

CT and MR perfusion imaging of the liver:techniques and clinical applications

GU Ai-hua

Department of Radiology, Shanghai Tenth People's Hospital, Shanghai Tongji University, Shanghai 200080, China
CLC number: R445.2

摘要: 近年来随着CT、MR功能成像研究的发展,国内外有不少学者尝试使用CT、MR肝脏灌注成像评价肝脏功能及肝脏病变的血液动力学特征。综述了近来国内外CT、MR灌注成像在肝脏评价中的应用现状,重点是图像分析方法及临床应用。
- 体层摄影术,X线计算机 /
- 磁共振成像 /
- 肝 /
- 灌注成像
Abstract: In recent years the functional imaging techniques of CT and MR including perfusion imaging have developed fast. Some studies are attempting to evaluate the hepatic function and the hemodynamic characteristics of the hepatic lesions by using CT or MR perfusion imaging. The purpose of this article is to review the recent studies of the applications of CT and MR perfusion imaging to the evaluation of the liver. The main topics are imaging analysis and clinical applications.
- Tomography X-rays,computed /
- Magnetic resonance imaging /
- Liver /
- Perfusion imaging
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

[1]	Axel L. Cerebral blood flow determination by rapid-sequence computed tomography:theoretical analysis. Radiology, 1980, 137:679-686.
[2]	Gulberg V, Haag K, Rossle M, et al. Hepatic arterial buffer response in patients with advanced cirrhosis. Hepatology, 2002,35(3):630-634.
[3]	Tsushima Y, Funabasama S, Sanada S, et al. Development of perfusion CT software for personal computers. Acad Radiol, 2002,9(8):922-926.
[4]	Annet L, Materne R, Danse E, et al. Hepatic flow parameters measured with MR imaging and Doppler US:correlations with degree of cirrhosis and portal hypertension. Radiology, 2003, 229(2):409-414.
[5]	Ichikawa T, Arbab AS, Araki T, et al. Perfusion MR imaging with a superparamagnetic iron oxide using T₂-weighted and susceptibility-sensitive echoplanar sequences:evaluation of tumor vascularity in hepatocellular carcinoma. AJR, 1999, 173(1):207-213.
[6]	Materne R, Smith AM, Peeters F, et al. Assessment of hepatic perfusion parameters with dynamic MRI. Magn Reson Med, 2002,47(1):135-142.
[7]	Van Beers BE, Leconte I, MaternetR, et al. Hepatic perfusion parameters in chronic liver disease:dynamic CT measurements correlated with disease severity. AJR, 2001, 176(3):667-673.
[8]	Peters AM, Brown J, Hartnell GG, et al. Non-invasive measurement of renal blood flow with 99mTc DTPA:comparison with radiolabelled microspheres. Cardiovasc Res, 1987, 21(11):830-834.
[9]	Tsushima Y, Blomley MJ, Kusano S, et al. Measuring portal venous perfusion with contrast-enhanced CT:comparison of direct and indirect methods. Acad Radiol, 2002, 9(3):276-282.
[10]	Blomley MJ, Coulden R, Dawson P, et al. Liver perfusion studied with uhrafast CT. J Comput Assist Tomogr, 1995, 19(3):424-433.
[11]	Materne R, Van Beers BE, Smith AM, et al. Non-invasive quantification of liver perfusion with dynamic computed tomography and a dual-input one-compartmental model. Clin Sci, 2000, 99(6):517-525.
[12]	Materne R, Annet L, Dechambre S, et al. Dynamic computed tomog-raphy with low-and high-molecular-mass contrast agents to assess microvascular permeability modifications in a model of liver fibrosis. Clin Sci, 2002, 103(2):213-216.
[13]	Van Beers BE, Materne R, Annet L, et al. Capillarization of the sinu-soids in liver fibrosis:noninvasive assessment with contrast-enhanced MRI in the rabbit. Magn Reson Med, 2003, 49(4):692-699.
[14]	Peeters F, Annet L, Hermoye Let al. Inflow correction of hepatic perfusion measurements using Tl-weighted, fast gradient-echo, contrast-enhanced MRI. Magn Reson Med, 2004, 51(4):710-717.
[15]	Weidekamm C, Cejna M, Kramer L, et al. Effects of TIPS on liver perfusion measured by dynamic CT. Am J Roentgenol, 2005, 184(2):505-510.
[16]	Tsushima Y, Unno Y, Koizumi J, et al. Hepatic perfusion changes af-ter transcatheter arterial embolization (TAE) of hepatocellular car-cinoma:measurement by dynamic computed tomography(CT). Dig Dis Sci, 1998, 43(2):317-322.
[17]	Tsushima Y, Funabasama S, Aoki J, et al. Quantitative perfusion map of malignant liver tumors, created from dynamic computed tomography data. Acad Radiol, 2004, 11(2):215-223.
[18]	Totman JJ, O'gorman RL, Kane PA, et al. Comparison of the hepatic perfusion index measured with gadolinium-enhanced volumetric MRI in controls and in patients with colorectal cancer.Br J Radiol, 2005, 78(926):105-109.
[19]	Fuentes MA, Keith CJ, Griffiths M, et al. Hepatic haemodynamics:interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indices. Br J Radiol, 2002, 75(889):17-23.
[20]	Pandharipande PV, Krinsky GA, Rusinek H, et al. Perfusion imaging of the liver with time-resolved, contrast-enhanced, whole-liver MRI (abstr). In:proceedings of the 11th Meeting of the international Society for Magnetic Resonance in Medicine, 2003, 1251.
[21]	Rusinek H, Lee VS, Johnson G. optimal dose of Gd-DTPA in dynamic MR studies. Magn Reson Med, 2001, 46(2):312-316.
[22]	McKenzie CA, Plato FS, Thornhill RE, et al. T(1) fast acquisition relaxation mapping (T[1]-FARM):optimized data acquisition. J Magn Reson Imaging, 2000, 18(2):129-138.
[23]	Kapanen MK, Halavaara JT, Hakkinen AM. Open four-concpartment model in the measwrement of liver perfusion. Acacl Radiol, 2005, 12(12):1542-1550.

[1]	于军 , 张莺 , 任东栋 , 陈聪 , 李洋 , 任春玲 , 蔡君 . ¹⁸F-FDG PET/CT与PET/MRI在结直肠癌肝转移诊断中的比较分析. 国际放射医学核医学杂志, 2021, 45(2): 75-82. doi: 10.3760/cma.j.cn121381-202003009-00013
[2]	周伶伶 , 梁瑞金 , 殷亮 . CT灌注成像联合血脑屏障损伤标志物对脓毒症相关性脑病的诊断价值. 国际放射医学核医学杂志, 2019, 43(3): 242-249. doi: 10.3760/cma.j.issn.1673-4114.2019.03.008
[3]	王静 , 姚振威 . 细胞磁共振成像技术在体示踪免疫细胞的研究进展. 国际放射医学核医学杂志, 2014, 38(5): 337-340. doi: 10.3760/cma.j.issn.1673-4114.2014.05.014
[4]	马彦云 , 张辉 . 磁共振体素内不相干运动扩散加权成像的原理及应用进展. 国际放射医学核医学杂志, 2016, 40(6): 469-473. doi: 10.3760/cma.j.issn.1673-4114.2016.06.013
[5]	闵捷 , 李斌 , 金凯 , 梁维仁 , 晁明 . 肝脏磁共振弹性成像的应用现状与展望. 国际放射医学核医学杂志, 2014, 38(4): 261-265. doi: 10.3760/cma.j.issn.1673-4114.2014.04.013
[6]	田海静 . 磁共振心肌灌注成像对急性心肌梗死的临床评价. 国际放射医学核医学杂志, 2007, 31(6): 388-388.
[7]	宋书扬 , 韩旭 , 汪蕾 , 闫朝武 , 方纬 . 核素心肌灌注/代谢显像与心脏磁共振成像评价缺血性心脏病心肌活力的对比研究. 国际放射医学核医学杂志, 2024, 48(1): 38-45. doi: 10.3760/cma.j.cn121381-202308010-00386
[8]	周翠屏 , 沈君 , 梁碧玲 . 干细胞移植的磁性标记及磁共振成像活体示踪. 国际放射医学核医学杂志, 2006, 30(4): 253-256.
[9]	冯苏洋 , 邢炯 , 舒敏 , 刘加成 . 抑郁症相关执行功能障碍的磁共振成像研究进展. 国际放射医学核医学杂志, 2021, 45(12): 795-799. doi: 10.3760/cma.j.cn121381-202012010-00117
[10]	杨晓棠 , 杨继虎 , 杜笑松 , 张建新 . 磁共振扩散加权成像及动态增强MRI在乳腺病变中的应用价值. 国际放射医学核医学杂志, 2011, 35(3): 189-193. doi: 10.3760/cma.j.issn.1673-4114.2011.03.014
[11]	李骁扬 , 田野 . 动态增强磁共振成像在抗肿瘤血管药物早期临床试验中的应用. 国际放射医学核医学杂志, 2014, 38(5): 309-314. doi: 10.3760/cma.j.issn.1673-4114.2014.05.008