<sup>99</sup>Tc<sup>m</sup>-AnnexinV用于体内细胞凋亡显像的研究进展

靳彩玲; 范我

⁹⁹Tc^m-AnnexinV用于体内细胞凋亡显像的研究进展

靳彩玲 , 范我

文章导航 > 国际放射医学核医学杂志 > 2005, 29 > 1: (23-26)

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⁹⁹Tc^m-AnnexinV用于体内细胞凋亡显像的研究进展

靳彩玲,
范我

215007 苏州, 苏州大学放射医学与公共卫生学院
中图分类号: R817.4

Advance of apoptosis imaging with ⁹⁹Tc^m labeled Annexin V

School of Radiation Medicine and Public Health, Suzhou University, Suzhou 215007, China
CLC number: R817.4

摘要: 细胞凋亡早期,磷脂酰丝氨酸从细胞膜脂双层的内层迁移至外层,利用⁹⁹Tc^m标记的AnnexinV对细胞凋亡暴露在细胞膜表面的磷脂酰丝氨酸进行体内显像,可检测早期细胞凋亡。
- ⁹⁹Tc^m-AnnexinV /
- 细胞凋亡 /
- 核素显像
Abstract: Phosphatidyl serine exposures on the outer leaflet of the plasma membrane lipid bilayer at the beginning of apoptosis, ⁹⁹Tc^m-labeled Annexin V is used to image in vivo the phosphatidyl serine that explode on the outer surface of cell membrane after apoptosis so that apoptosis can be detected on the early stage.
- Tcm-Annexin V /
- apoptosis /
- radionuclide imaging
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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