氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究

蔡莉; 李彦生

蔡莉 , 李彦生

文章导航 > 国际放射医学核医学杂志 > 2005, 29 > 1: (10-14)

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氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究

蔡莉,
李彦生

300052 天津, 天津医科大学总医院PET-CT中心
中图分类号: R817.4

Comparison of ¹⁸F-FDG and amino acid PET imaging in brain tumors

PET-CT Center, Tianjin Medical University General Hospital, Tianjin 300052, China
CLC number: R817.4

摘要: 脑肿瘤细胞生长速率加快,能量代谢、氨基酸转运和蛋白质合成旺盛。联合¹⁸F-FDG与¹¹C-MET的PET,比单一显像剂更有助于脑肿瘤的组织学分级、术后复发和疗效评价。¹¹C-MET较¹⁸F-FDG能更精确地显示肿瘤扩散范围和轮廓,对制订手术和立体定向放疗计划有重要意义,是常规CT和(或)MRI的有益补充。
- ¹⁸F-氟代脱氧葡萄糖 /
- ¹¹C-甲硫氨酸 /
- 正电子发射体层显像 /
- 脑肿瘤 /
- 对比研究
Abstract: Energy metabolism and amino acid transport and incorporation are important components of the pathophysiology of brain tumors. Combination of ¹⁸F-FDG and amino acid, especially ¹¹C-MET is more useful than single tracer in the field of brain tumor grading, differential diagnosis recurrent tumor from radiation necrosis and evaluation of prognosis. In addition, ¹¹C-MET is better than ¹⁸F-FDG in delineating tumor boundary, so it can provides more exact information in biopsy localization and planning of radiosurgery.
- F-fluorodeoxyglucose /
- ¹¹C-methionine /
- positron emission tomography /
- brain tumor /
- comparison study
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究

蔡莉
李彦生

300052 天津, 天津医科大学总医院PET-CT中心

收稿日期: 2004-10-09

关键词:

摘要: 脑肿瘤细胞生长速率加快,能量代谢、氨基酸转运和蛋白质合成旺盛。联合¹⁸F-FDG与¹¹C-MET的PET,比单一显像剂更有助于脑肿瘤的组织学分级、术后复发和疗效评价。¹¹C-MET较¹⁸F-FDG能更精确地显示肿瘤扩散范围和轮廓,对制订手术和立体定向放疗计划有重要意义,是常规CT和(或)MRI的有益补充。