电离辐射的非靶效应和延迟效应

左雅慧; 童建

电离辐射的非靶效应和延迟效应

左雅慧 , 童建

文章导航 > 国际放射医学核医学杂志 > 2007, 31 > 3: (176-179)

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电离辐射的非靶效应和延迟效应

左雅慧¹,
童建^2, ,

1. 030006 太原, 中国辐射防护研究院放射医学与环境医学研究所辐射生物效应研究室;
2. 215123 苏州, 苏州大学放射医学与公共卫生学院卫生毒理学教研室

通讯作者: 童建, tongjian@suda.edu.cn

中图分类号: Q691.5

Non-targeted and delayed effects of exposure to ionizing radiation

ZUO Ya-hui¹,
TONG Jian^2, ,

1. Laboratory of Radiobiobgy, Division of Radiology and Environental Medicine, China Institute for Radiation Protection, Taiyuan 030006, China;
2. Department of Toxicology, School of Radiation Medicine and Public Health, Soochow University, Suzhou 215123, China

Corresponding author: TONG Jian, tongjian@suda.edu.cn

CLC number: Q691.5

摘要: 电离辐射的非靶效应和延迟效应是细胞对电离辐射反应的两种相互关联的表现.目前,对这两种效应的研究主要集中在辐射诱发的基因组不稳定性、旁效应、适应性反应三个方面.随着研究的深入,非靶效应和延迟效应在低剂量辐射效应领域越来越受到重视.为此对这两种效应的相互关系及其潜在的生物学意义作一简述.
- 辐射,电离 /
- 辐射效应 /
- 辐射剂量
Abstract: Non-targeted and delayed effects are relative phenomena in cellular responses to ionizing radiation.These effects (bystander effects, genomic instability and adaptive responses) have been studied most extensively for radiation exposures. It is clear that adaptive responses, bystander effects and genomic instability will play an important role in the low dose-response to radiation. This review will provide a synthesis of the known, and proposed interrelationships amongst low-dose cellular responses to radiation. It also will examine the potential biological significance of non-targeted and delayed effects of exposure to ionizing radiation.
- Radiation,ionizing /
- Radiation effects /
- Radiation dosage
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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电离辐射的非靶效应和延迟效应

左雅慧¹
童建^2, ,

通讯作者: 童建, tongjian@suda.edu.cn

1. 030006 太原, 中国辐射防护研究院放射医学与环境医学研究所辐射生物效应研究室;
2. 215123 苏州, 苏州大学放射医学与公共卫生学院卫生毒理学教研室

收稿日期: 2007-01-09

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摘要: 电离辐射的非靶效应和延迟效应是细胞对电离辐射反应的两种相互关联的表现.目前,对这两种效应的研究主要集中在辐射诱发的基因组不稳定性、旁效应、适应性反应三个方面.随着研究的深入,非靶效应和延迟效应在低剂量辐射效应领域越来越受到重视.为此对这两种效应的相互关系及其潜在的生物学意义作一简述.