SPECT脑血流灌注显像和受体显像对抑郁症的研究

原凌 刘建中 武志芳

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SPECT脑血流灌注显像和受体显像对抑郁症的研究

  • 中图分类号: R814.42;R749.4

The study of SPECT cerebral blood flow and neuroreceptor imaging in depressive disorders

  • CLC number: R814.42;R749.4

  • 摘要: 抑郁症的影像学检查有结构性脑成像和功能性脑成像,CT和MRI检查脑结构的异常既不显著又不具有特异性,而PET和SPECT提供了在活体内对抑郁症进行局部脑血流灌注和中枢神经递质与受体结构和功能的研究,为进一步探讨抑郁症的病因、发病机制以及临床治疗提供客观依据.
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    [15] Bonne O, Krausz Y, Gorfine M, et al. Cerebral hypopeffusion in medication resistant, depressed patients assessed by Tc-99m HMPAO SPECT. J Affect Disord. 1996, 41(3):163-171.
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    [19] Willeit M. Praschak-Rieder N, Neumeister A, et al.[123I]-[beta]-CIT SPECT imaging shows rednced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder. Biol Psychiatry, 2000, 47(6):482-489.
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  • 收稿日期:  2007-02-26

SPECT脑血流灌注显像和受体显像对抑郁症的研究

  • 030001 太原, 山西医科大学第一医院核医学科

摘要: 抑郁症的影像学检查有结构性脑成像和功能性脑成像,CT和MRI检查脑结构的异常既不显著又不具有特异性,而PET和SPECT提供了在活体内对抑郁症进行局部脑血流灌注和中枢神经递质与受体结构和功能的研究,为进一步探讨抑郁症的病因、发病机制以及临床治疗提供客观依据.

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