2DE技术及其在辐射损伤研究中的应用

王治东; 陈肖华

2DE技术及其在辐射损伤研究中的应用

王治东 , 陈肖华

文章导航 > 国际放射医学核医学杂志 > 2003, 27 > 1: (45-47)

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2DE技术及其在辐射损伤研究中的应用

王治东¹,
陈肖华²

1. 100850 北京, 军事医学科学院放射医学研究所放射病实验治疗研究室;
2. 100850 北京, 军事医学科学院放射医学研究所

作者简介: 王治东(1977-),男,硕士研究生,主要从事辐射血液学研究。;陈肖华(1958-),男,副研究员,主要从事放射病实验治疗研究。;

中图分类号: Q5-33;R818.23

Progress in two-dimensional polyacrylamide gelelectrophoresis and applicationin in radiation research

WANG Zhi-dong¹,
CHEN Xiao-hua²

Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China
CLC number: Q5-33;R818.23

摘要: 2DE(二维聚丙烯酰胺凝胶电泳)技术是蛋白质组学研究中的主要分离技术,其分别以蛋白质的等电点和分子质量这两个独立的参数为基础,实现蛋白质混合物的分离。2DE在探讨疾病发生机理,寻找肿瘤早期诊断指标,及药物开发研究等方面均有较好的应用,在辐射损伤研究中的应用也有广泛的前景。
- 蛋白质分离 /
- 二维聚丙烯酰胺 /
- 辐射损伤
Abstract: Two-dimensional polyacrylamide gel electrophoresis is the key separation technique in proteomics research, which is designed by protein character:molecular weight and PI. Some progress has been made in disease mechanism detection, tumour indicator research and drug development. This technique also has some potential application in radiation research.
- protein separation /
- two-dimensional polycrylamide gel electrophoresis /
- irradiation
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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