肿瘤辐射增敏机制研究进展

李玉; 董丹; 阎英

肿瘤辐射增敏机制研究进展

李玉 , 董丹 , 阎英

文章导航 > 国际放射医学核医学杂志 > 2007, 31 > 1: (48-50)

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肿瘤辐射增敏机制研究进展

1. 110015 沈阳, 沈阳军区总医院放射治疗科;
2. 116027 大连, 大连医科大学临床系

通讯作者: 董丹, dongdan1026@163.com ;

中图分类号: R811.5

The development of radiosensitizer mechanisms

1. Department of Radiotherapy, General Hospital of Shenyang Military Command, Shenyang 110015, China;
2. Department of Clinical, Dalian Medical University, Dalian 116027, China

Corresponding author: DONG Dan, dongdan1026@163.com ;

CLC number: R811.5

摘要: 辐射增敏作用机制非常复杂,迄今为止尚无明确的解释。其机制主要包括改变肿瘤微环境、清除自由基和电子、细胞周期同步化、抑制DNA损伤修复、促进细胞凋亡和生物还原作用。辐射增敏作用机制的研究在提高肿瘤放疗效果方面具有重要的理论指导意义。
- 肿瘤 /
- 辐射增敏药 /
- 放射疗法
Abstract: Mechanism of radiosensitivity is very complex, there has been no definite explanation up to now. According to literatures, changing tumor microenvironment, clear free radical and electron, making cell cycle synchronization, suppressing repairment of DNA injury, promoting apoptosis and biological reduction are the main mechanisms. Studying mechanisms of radiosensitivity will help to improve the effect of radiotherapy.
- Neoplasms /
- Radiosensitizing agents /
- Radiotherapy
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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