放射性核素反义技术在肿瘤治疗中的研究
Application of the radionuclide antisense technique in the treatment of tumors
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摘要: 放射性核素反义治疗是放射性核素产生辐射生物效应杀伤病变细胞与反义寡核苷酸链阻断基因表达相结合而达到治疗疾病的目的,具有特异性强、靶向性高和损伤性小等优点,为肿瘤的治疗提供了新方法。Abstract: Radionuclide antisense technique, which combined radiation biological effect with antisense therapy, treats polygenic diseases, especially tumors. Antisense oligonucleotide labeled with radionuclide can target abnormal gene specially, thus radiation biological effect takes place in the abnormal part of cells, and does not damage normal part of cells. This will be a new way in the treatment of diseases.
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Key words:
- Radioisotopes /
- Oligonucleotdes,antisense /
- Radiation oncology
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