微核着丝粒的荧光原位杂交技术在辐射研究中的应用

田素青

田素青

文章导航 > 国际放射医学核医学杂志 > 2002, 26 > 2: (83-86)

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微核着丝粒的荧光原位杂交技术在辐射研究中的应用

田素青

300192 天津, 中国医学科学院中国协和医科大学放射医学研究所

作者简介: 田素青(1977-),男,山东鱼台人,硕士研究生,主要研究方向:分子流行病学。;

中图分类号: Q345⁺.2

The applications of the centromere micronucleus using FISH in radiation research

TIAN Su-qing

Institute of Radiation Medicine Chinese Academy of Medical Sciences, Peking Union Medical College, Tianjin 300192, China
CLC number: Q345⁺.2

摘要: 微核分析因其在遗传毒理学和辐射生物剂量学中的广泛应用而受到人们关注。近年来,随着分子遗传学及荧光原位杂交(FISH)技术的发展,人们对微核有了进一步的认识。FISH技术能用于解释微核的形成机理、功能及微核的超微结构,并可用于辐射损伤的遗传学评价。
- 微核 /
- 荧光原位杂交技术 /
- 辐射损伤
Abstract: The micronucleus assay is widely used both in genetic toxicology and in the radiation biomonitoring of human population. With the development of molecular genetics and fluorescence in situ hybridization (FISH), more have been known about micronucle. FISH can be used to interpret the formation mechanism, the function and the ultrastructure of the micronucleus, as well as the genetic evaluation of radiation damage.
- micronucleus /
- fluorescence in situ hybridization technology /
- radiation damage
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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