富勒烯及其衍生物在核生物医学领域应用的研究现状

倪瑾; 蔡建明; 吴秋业

倪瑾 , 蔡建明 , 吴秋业

文章导航 > 国际放射医学核医学杂志 > 2006, 30 > 2: (72-75)

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富勒烯及其衍生物在核生物医学领域应用的研究现状

1. 200433 上海, 第二军医大学放射医学教研室;
2. 200433 上海, 第二军医大学药学院有机化学教研室
基金项目:
国家自然科学基金资助项目(30200069)
中图分类号: R817.9

The research status of empty and metallofullerene derivatives for biological applications

1 Department of Rculiation Medicine;Second Military Medical University, Shanghai 200433, China;
2. Department of Organic Chemistry;Second Military Medical University, Shanghai 200433, China
CLC number: R817.9

摘要: 富勒烯及其衍生物是一类具有独特物理化学特性的化合物,在生物医学领域有广泛的应用前景。介绍该类化合物的合成及制备,富勒烯笼外配合物的抗HIV病毒、断裂DNA和清除自由基等生物学活性,以及富勒烯金属包合物在核医学诊断中的应用研究。
- 烯烃类 /
- 生物学标记 /
- 诊断显像 /
- 富勒烯
Abstract: Fullerenes are a class of compounds with unique chemical and physical properties, which potential uses can be explored in the biological medicine field. The review reports the synthesis and preparation of the compounds; the biological effects of empty fullerenes in anti-HIV, DNA cleavage, radical scavenger and recent aspects of metallofullerene as nuclear radiomedicine for diagnosis and treatment of diseases.
- Alkenes /
- Biological markers /
- Diagnostic imaging /
- Fullerene
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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