单细胞凝胶电泳在放射医学中的应用

洪承皎; 张军宁

单细胞凝胶电泳在放射医学中的应用

洪承皎 , 张军宁

文章导航 > 国际放射医学核医学杂志 > 2000, 24 > 6: (281-284)

引用本文:

Citation:

单细胞凝胶电泳在放射医学中的应用

215007 苏州, 苏州大学核医学院

作者简介: 洪承皎(1966-),女,江苏苏州人,苏州大学核医学主管技师。;张军宁(1966-),男,陕西耀县人,苏州大学附属第-医院博士研究生,主要从事肿瘤放射治疗的基础及临床研究。;

中图分类号: R818.0

Applications of single cell gel electrophoresis assay in radiation research

School of medicine, Suzhou university, Suzhou, China
CLC number: R818.0

摘要: 单细胞凝胶电泳是一种在单细胞水平检测哺乳类有核细胞DNA断裂的新技术。本文着重介绍了该技术在DNA辐射损伤、辐射致突致癌分子机制、自由基清除与辐射效应阻断药物、辐射剂量估算、肿瘤放射敏感性的预测、辐射诱发细胞凋亡的研究中的应用进展。
- 单细胞凝胶电泳 /
- DNA损伤 /
- 电离辐射
Abstract: The single cell gel electrophoresis (SCGE), also called comet assay, is a sensitive and rapid method forDN A damage detection in individual mammalian cell.Its use has increased significantly in the past few years.Applications in the field of radiation medicine are reviewed and possible future directions of the technique arebriefly explored.
- single cell gel electrophoresis /
- DNA strand break /
- ionizing radiation
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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