<sup>11</sup>C-flumazenil PET对癫痫灶定位诊断的价值

胡四龙

¹¹C-flumazenil PET对癫痫灶定位诊断的价值

胡四龙

文章导航 > 国际放射医学核医学杂志 > 2000, 24 > 6: (249-254)

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¹¹C-flumazenil PET对癫痫灶定位诊断的价值

胡四龙

200040 上海, 复旦大学医学院附属华山医院核医学科

作者简介: 胡四龙(1970-),男,湖北通城人,复旦大学医学院附属华山医院核医学科硕士研究生,主要从事肾脏核医学显像研究。;

中图分类号: R817.4

The evaluation of ¹¹C-flumazenil PET in the localisation of epileptic foci

HU Silong

Department of Nuclear Medicine, Huashan Hospital, Medical Center of Fudan University, Shanghai, China
CLC number: R817.4

摘要: ¹¹C-flumazenil(¹¹C-FMZ)PET所测量到的局部脑区中枢型苯二氮受体(cBZR)密度降低是癫痫灶的特异性生化改变的标志,对癫痫灶定位的灵敏度和准确性高,明显优于EEG(脑电图)、MRI、¹⁸F-FDG PET(¹⁸F-氟代脱氧葡萄糖)等方法。
- 癫痫灶 /
- ¹¹碳-氟马西尼 /
- 正电子发射断层显像 /
- 中枢型苯二氮受体
Abstract: the density of central benzodiazepine (cBZR) receptor is significanly reduced in epileptic foci and it is regdarded as the specific biochemical marker of epileptic foci.¹¹C-flumazenil PET can measure the cBZR desity and is superior to MRI and ¹⁸F-FDG in accurate presurgical identification of epileptic foci.
- epilpsy, focus /
- ¹¹C-flumazenil /
- positron emission tomography /
- central benzodiazepine receptor(cBZR)
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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