PET预测及评价肿瘤疗效的新进展

闫瑾; 林祥通

PET预测及评价肿瘤疗效的新进展

闫瑾 , 林祥通

文章导航 > 国际放射医学核医学杂志 > 2006, 30 > 4: (214-217)

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PET预测及评价肿瘤疗效的新进展

闫瑾,
林祥通

200040 上海, 复旦大学附属华山医院核医学科
中图分类号: R817.4

The new advance of prediction and evaluation of tumor therapeutic effects by PET

Department of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China
CLC number: R817.4

摘要: 临床上评价及预测肿瘤疗效的手段很多,包括体格检查、普通影像学检查(X线摄片、CT、MRI等)和肿瘤标志物检测等,但这些方法均有很大的局限性,如主观性强、敏感性差等。PET可以早期准确地反映肿瘤相关生物特征,如血管生成、凋亡、乏氧和增殖等。因此,利用相应的可反映上述生物特征的显像剂行PET,可对肿瘤进行早期诊断、评价和预测肿瘤治疗的疗效,协助临床医生制定治疗方案。
- 体层摄影术,发射型计算机 /
- 血管生成 /
- 细胞凋亡 /
- 低氧 /
- 增殖
Abstract: There are many methods that evaluate and predicate the therapeutic effects of tumors, including physical examination, common imaging (X-ray, CT, MRI etc) and tumor marker etc. But these methods have many limits, for example:more subjective, less sensitivity etc. The relative biological features as angiogenesis, apoptosis, hypoxic and proliferation can be reflected by PET early and correctly. So, we can diagnose tumor, predict and evaluate its therapeutic effects by PET used the accorded tracers that reflect the above biological features. Helping clinical doctors to make therapeutic methods.
- Tomography, emission-computed /
- Angiogenesis /
- Apoptosis /
- Hypoxia /
- Proliferation
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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PET预测及评价肿瘤疗效的新进展

闫瑾
林祥通

200040 上海, 复旦大学附属华山医院核医学科

收稿日期: 2006-04-29

关键词:

摘要: 临床上评价及预测肿瘤疗效的手段很多,包括体格检查、普通影像学检查(X线摄片、CT、MRI等)和肿瘤标志物检测等,但这些方法均有很大的局限性,如主观性强、敏感性差等。PET可以早期准确地反映肿瘤相关生物特征,如血管生成、凋亡、乏氧和增殖等。因此,利用相应的可反映上述生物特征的显像剂行PET,可对肿瘤进行早期诊断、评价和预测肿瘤治疗的疗效,协助临床医生制定治疗方案。