基因转移技术与基因靶向性核素治疗

王佳琼; 王自正

基因转移技术与基因靶向性核素治疗

王佳琼 , 王自正

文章导航 > 国际放射医学核医学杂志 > 2004, 28 > 4: (145-149)

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基因转移技术与基因靶向性核素治疗

210006 南京, 南京医科大学附属南京市第一医院临床核医学中心
中图分类号: R817.5

Gene transfer technology and genetic radioisotope targeting therapy

Department of Nuclear Medicine, Nanjing First Hospital Affiliated Nanjing Medical University, Nanjing 210006, China
CLC number: R817.5

摘要: 随着在细胞分子水平上对疾病发病机制认识的深入,基因治疗已成为目前医学分子生物学最重要的研究领域之一。基因治疗过程中基因转移技术起着关键作用,携带目的基因的载体有待进一步开发和改进。在基因治疗过程中,需要进行基因监测,基因显像是其最有效的方法。将基因治疗与靶向核素治疗相结合,即"基因靶向核素治疗"为肿瘤基因治疗开辟了一条崭新的途径。
- 基因转移载体 /
- 基因显像 /
- 基因治疗 /
- 基因靶向核素治疗
Abstract: With deeper cognition about mechanisms of disease at the cellular and molecular level, gene therapy has become one of the most important research fields in medical molecular biology at present. Gene transfer technology plays an important role during the course of gene therapy, and further improvement should be made about vectors carrying target gene sequences. Also, gene survey is needed during gene therapy, and gene imaging is the most effective method. The combination of gene therapy and targeted radiotherapy, that is,"Genetic Radioisotope Targeting Therapy", will be a novel approach to tumor gene therapy.
- gene transfer vector /
- gene imaging /
- gene therapy /
- genetic radioisotope targeting therapy
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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基因转移技术与基因靶向性核素治疗

210006 南京, 南京医科大学附属南京市第一医院临床核医学中心

收稿日期: 2004-05-19

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摘要: 随着在细胞分子水平上对疾病发病机制认识的深入,基因治疗已成为目前医学分子生物学最重要的研究领域之一。基因治疗过程中基因转移技术起着关键作用,携带目的基因的载体有待进一步开发和改进。在基因治疗过程中,需要进行基因监测,基因显像是其最有效的方法。将基因治疗与靶向核素治疗相结合,即"基因靶向核素治疗"为肿瘤基因治疗开辟了一条崭新的途径。