腹部肿瘤精确放疗准确性的影响因素

杨铁明; 鞠永健

腹部肿瘤精确放疗准确性的影响因素

杨铁明 , 鞠永健

文章导航 > 国际放射医学核医学杂志 > 2008, 32 > 6: (360-362,378)

引用本文:

Citation:

腹部肿瘤精确放疗准确性的影响因素

226001 江苏, 江苏省南通市第一人民医院放疗科
基金项目:
江苏省自然科学基金(BK2007553)

国家自然科学基金(10705016)

Factors that affect the accuracy in the precise radiotherapy for abdomen tumors

Department of Radiotherapy, The First People's Hospital of Nantong City, Jiangsu Nantong 226001, China

摘要: 精确放疗在临床已得到广泛应用,但在实施过程中存在很多影响放疗准确性的因素,最终可明显影响治疗效果。腹部肿瘤精确放疗过程中存在不确定性因素,总结以往的研究数据,分析呼吸运动、摆位、体位及同定技术、体重、肿瘤自身退缩及肿瘤周围器官运动与充盈等情况对精确放疗的影响,有助于对临床工作中要注意的问题进行探讨。
- 腹部肿瘤 /
- 放射疗法 /
- 不确定性
Abstract: The precise radiotherapy has been widely used in the clinics. But there are many factors that affect the accuracy in the course of implementation. Finally the effect of radiotherapy is affected. These factors are reviewed. And the previous research data about the abdomen tumors is summed up. Also how the accuracy was affected by the respiratory movement, positioning, position fixed technology, weight, retraction and motion of the tumor and the situation of surrounding organs will be analyzed. At last, how to avoid these errors in clinics will be discussed.
- Abdomen neoplasms /
- Radiotherapy /
- Inaccuracy
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

[1]	Bussels B,Go ethals L,Feron M,et al. Respiration-induced movement of the upper abdominal organs:a pitfall for the three-dimensional conformal radiation treatment of pancreatic cancer[J]. Radiother Oncol,2003,68(1):69-74.
.[25] Nuyttens JJ,Robertson JM,Yan D,et al. The variability of the clinical target volume for rectal cancer due to internal organ motion during adjuvant treatment[J]. Int J Radiat Oncol Biol Phys,2002,53(2):497-503.
[3]	Kim YS,Park SH,Ahn SD,et al. Differences in abdominal organ movement between supine and prone positions measured using four-dimensional computed tomography[J]. Radiother Oncol,2007,85(3):424-428.
[4]	Jacobs I,Vanregemorter J,Scalliet P. Influence of respiration on calculation and delivery of the prescribed dose in external radiotherapy[J]. Radiother Oncol,1996,39(2):123-128.
[5]	Keall PJ,Mageras GS,Balter JM,et al. The management of respiratory motion in radiation oncology report of AAPM Task Group 76[J]. Med Phys,2006,33(10):3874-3900.
[6]	Simon L,Giraud P,Servois V,et al. Comparative study and clinical implementation of two breathing-adapted radiotherapy techniques:dosimetric benefits for lung cancer treatment[J]. Cancer Radiother,2006,10(6-7):370-376.
[7]	Korreman SS,Juhler-Nøttrup T,Boyer AL. Respiratory gated beam delivery cannot facilitate margin reduction,unless combined with respiratory correlated image guidance[J]. Radiother Oncol,2008,86(1):61-68.
[8]	Mutaf YD,Brinkmann DH. Optimization of internal margin to account for dosimetric effects of respiratory motion[J]. Int J Radiat Oncol Biol Phys,2008,70(5):1561-1570.
[9]	胡逸民.肿瘤放射物理学[M].北京:原子能出版社,1999:456-466.
[10]	Hurkmans CW,Remeijer P,Lebesque JV,et al. Set-up verification using portal imaging; review of current clinical practice[J]. Radiother Oncol 2001,58(2):105-120.
[11]	Hoogeman MS,van Herk M,de Bois J, et al Strategies to reduce the systematic error due to tumor and rectum motion in radiotherapy of prostate cancer[J],Radiother Oncol,2005,74(2):177-185.
[12]	邱梅.腹部肿瘤放疗使用固定器价值的探讨[J].现代肿瘤医学,2004,12(6):580.
[13]	Lee S,Yang DS,Choi MS,et al. Development of respiratory motion reduction device system (RMRDs)for radiotherapy in moving tumors[J]. Jpn J Clin Oncol,2004,34(11):686-691.
[14]	Horst E,Micke O, Moustakis C,et al. Conformal therapy for pancreatic cancer:variation of organ position due to gastrointestinal disten-tion-implications for treatment planning[J]. Radiology,2002,222(3):681-686.
[15]	刘跃平,刘新帆,李晔雄,等.前列腺癌三维适形放疗体位对靶区和正常组织体积及照射剂量的影响[J].中华放射肿瘤学杂志,2005,14(5):422-426.
[16]	Wulf J,Hädinger U,Oppitz U,et al. Impact of target reproducibility on tumor dose in stereotactic radiotherapy of targets in the lung and liver[J].Radiother Oncol,2003,66(2):141-150.
[17]	吴丽鹏.食管癌三维适形放疗中肿瘤靶区移位及剂量学研究[D].河北医科大学硕士研究生学位论文,2007.
[18]	胡逸民,杨定宇.肿瘤放射治疗技术[M].北京:北京医科大学中国协和医科大学联出版社,1999:120-133.
[19]	Fiorino C,Foppiano F,Franzone P,et al. Rectal and bladder motion during conformal radiotherapy after radical prostatectomy[J]. Radiother Oncol,2005,74(2):187-195.
[20]	Muren LP,Smaaland R,Dahl O. Conformal radiotherapy of urinary bladder cancer[J]. Radiother Oncol,2004, 73(3):387-398.
[21]	Georg P,Georg D,Hillbrand M,et al. Factors influencing bowel sparing in intensity modulated whole pelvic radiotherapy for gynaecological malignancies[J]. Radiother Oncol,2006,80(1):19-26.
[22]	Kim TH,Chie EK,Kim DY,et al. Comparison of the belly board device method and the distended bladder method for reducing irradiated small bowel volumes in preoperative radiotherapy of rectal cancer patients[J]. Int J Radiat Oncol Biol Phys,2005,62(3):769-775.
[23]	Skala M,Berry M,Duchesne G,et al. Australian and New Zealand three-dimensional conformal radiation therapy consensus guidel-ines for prostate cancer[J],Australas Radiol,2004,48(4):493-501.
[24]	Koper PC,Heemsbergen WD,Hoogeman MS,et al. Impact of volume and location of irradiated rectum wall on rectal blood loss after radiotherapy of prostate cancer[J]. Int J Radiat Oncol Biol Phys,2004,58(4):1072-1082.
[25]	Leong T,Willis D,Joon DL,et al. 3D conformal radiotherapy for gastric cancer-results of a comparative planning study[J],Radiother Oncol,2005,74(3):301-306

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腹部肿瘤精确放疗准确性的影响因素

226001 江苏, 江苏省南通市第一人民医院放疗科

收稿日期: 2008-06-23

基金项目: 江苏省自然科学基金(BK2007553)国家自然科学基金(10705016)

关键词:

摘要: 精确放疗在临床已得到广泛应用,但在实施过程中存在很多影响放疗准确性的因素,最终可明显影响治疗效果。腹部肿瘤精确放疗过程中存在不确定性因素,总结以往的研究数据,分析呼吸运动、摆位、体位及同定技术、体重、肿瘤自身退缩及肿瘤周围器官运动与充盈等情况对精确放疗的影响,有助于对临床工作中要注意的问题进行探讨。