心肌活力测定的研究进展

王勤奋

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心肌活力测定的研究进展

  • 213003 常州, 苏州大学附属第三医院核医学科

  • 中图分类号: R817.4

The progress of research on the assessment of viable myocardium

  • Department of Nuclear Medicine, First Central Hospital, Tianjin 300192, China

  • CLC number: R817.4

  • 摘要: 心肌灌注显像的定量分析、门控心肌灌注显像、18F-氟代脱氧葡萄糖(18F-FDG)+99Tcm甲氧基异丁基异腈(99Tcm-MIBI)双核素同时采集(DISA)、介入心动图和核磁共振显像(MRI)技术的进展提高了对心肌活力的认识,介入心动图、心肌灌注显像、心肌代谢显像的结合应用提高了心肌活力测定的准确性。心肌活力测定可确定能得益于冠状动脉再血管化治疗的患者,并可预测术后左室射血分数的增加和心力衰竭症状的改善。
    Abstract: The techniques development of myocardial perfusion imaging quantitative analysis, gated SPECT imaging, 18F-fluorodeoxyglucose(18F-FDG) and 99Tcm-sestamibi(99Tcm-MIBI) dual isotope simultaneous acquisition (DISA), interventional echocar-diography and magnetic resonance imaging (MRI) have enhanced the recognition of myocardium viability. The combined applications of interventional echocardiography, myocardial perfusion imaging and myocardial metabolic imaging may improve accuracy for assessing viability. The assessment of myocardial viability allows identification of patients who are most likely to benefit from coronary revascularization, and prognosis of increase in left ventricular ejection fraction (LVEF) and improvement in heart failure symptoms postopera-tively.
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    [8] Zafrir N, Arditi A, Ben-Gal T, et al. Additive value of low-dose dobutamine to technetium-99m sestamibi-gated single-photon emission computed tomography for prediction of wall motion improvement in patients undergoing coronary artery bypass graft[J]. Clin Cardiol,2003, 26(11):530-535.
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  • 收稿日期:  2004-11-26

心肌活力测定的研究进展

  • 213003 常州, 苏州大学附属第三医院核医学科
  • 收稿日期: 2004-11-26

摘要: 心肌灌注显像的定量分析、门控心肌灌注显像、18F-氟代脱氧葡萄糖(18F-FDG)+99Tcm甲氧基异丁基异腈(99Tcm-MIBI)双核素同时采集(DISA)、介入心动图和核磁共振显像(MRI)技术的进展提高了对心肌活力的认识,介入心动图、心肌灌注显像、心肌代谢显像的结合应用提高了心肌活力测定的准确性。心肌活力测定可确定能得益于冠状动脉再血管化治疗的患者,并可预测术后左室射血分数的增加和心力衰竭症状的改善。

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