双时相18F-FDG PET在肿瘤良恶性鉴别诊断中的应用

尹立杰

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双时相18F-FDG PET在肿瘤良恶性鉴别诊断中的应用

  • 210029 南京, 南京医科大学第一附属医院心脏科

  • 中图分类号: R817.4

Application of dual time point 18F-FDG PET imaging in differentiating malignant from inflammatory lesions

  • Department of Nuclear Medicine, The First Hospital Affiliated Suzhou University, Suzhou 215006, China

  • CLC number: R817.4

  • 摘要: 18F-FDGPET已较广泛地用于对恶性肿瘤的诊断和临床分期。常规显像一般用单次显像所测SUV(标准化摄取值)来鉴别良恶性病变,但两者SUV之间有一定交叉,存在一定局限性。而依据不同类型细胞18F-FDG摄取速率不同的机制,进行双时相18F-FDGPET(早期显像加延迟显像),简单而实用,具有较高的灵敏度、特异性和准确性。
    Abstract: The 18F-FDG PET has been used extensively in the diagnosis and staging of several types of malignancies. In general, standardized uptake values (SUV)in single time point imaging has been used for separating malignant from benign lesions, nevertheless there is considerable overlap be, tween SUV of them, thereby limiting specificity of this method. According to various cell types exhibit varying rates of 18F-FDG uptake, performing dual time point imaging (scan 1 and scan 2)appears to be useful in differentiating malignant from benign lesions. This protocol is a simple and practical method with high sensitivity, high specificity and good accuracy for detection of malignant lesions.
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    [10] Huang SC. Anotomy of SUV[J]. Nucl Med Biol, 2000, 27:643-646.
    [11] Hustinx R, Smith R J, Benard F, et al. Can the standardized uptake value characterize primary brain tumors on FDGPET?[J]. EurJ Nucl Med, 1999, 26:1501-1509.
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  • 收稿日期:  2003-09-08

双时相18F-FDG PET在肿瘤良恶性鉴别诊断中的应用

  • 210029 南京, 南京医科大学第一附属医院心脏科
  • 收稿日期: 2003-09-08

摘要: 18F-FDGPET已较广泛地用于对恶性肿瘤的诊断和临床分期。常规显像一般用单次显像所测SUV(标准化摄取值)来鉴别良恶性病变,但两者SUV之间有一定交叉,存在一定局限性。而依据不同类型细胞18F-FDG摄取速率不同的机制,进行双时相18F-FDGPET(早期显像加延迟显像),简单而实用,具有较高的灵敏度、特异性和准确性。

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