18F—多巴PET在帕金森病中的应用
The Applications of 18F-DOPA PET in Parkinson's Disease
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摘要: 黑质纹状体多巴胺能神经通路的受损是帕金森病(PD)发病机制中的主要因素,18F-多巴PET可以反映黑质纹状体神经元的结构和生化特性,这对于PD的早期诊断、鉴别诊断、病程评价和预后估计有重要的作用。Abstract: The injury of the presynaptic nigrostriatal dopaminergic projection is the important mechanism of Parkinson's disease(PD). 18F-DOPA PET provides a measure of the structure as well as the biochemical iategrity of the dopaminergic ueurous, which contribute to the early diagnosis, differentiation diagnosis, prognosis evaluation of PD.
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Key words:
- parkinson's disease /
- 18F-DOPA /
- positron emission tomography
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