放射性籽源薄层片植入治疗肿瘤的研究进展

于雷; 陈红红; 程文英; 邵春林

放射性籽源薄层片植入治疗肿瘤的研究进展

于雷 , 陈红红 , 程文英 , 邵春林

文章导航 > 国际放射医学核医学杂志 > 2006, 30 > 6: (369-372)

引用本文:

Citation:

放射性籽源薄层片植入治疗肿瘤的研究进展

200032 上海, 上海复旦大学放射医学研究所放射生物部

通讯作者: 陈红红, hhchen@shmu.edu.cn ;

基金项目:
上海市科委重点科技攻关项目(045211026)
中图分类号: R730.55

Progress of intraoperative brachytherapy using radioactive seeds plaque implants for tumor

Department of Radiation Biology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, China

Corresponding author: CHEN Hong-hong, hhchen@shmu.edu.cn ;

CLC number: R730.55

摘要: 将放射性籽源固定于一定的载体材料中制成放射性籽源薄层片、在瘤床或肿瘤表面植入进行近距离放射治疗的方法有其独特的优点,它可以优化空间剂量分布、减少籽源移位、扩大临床适应证及方便实施治疗,从而取得更好的疗效,具有良好的临床应用前景。
- 碘放射性同位素 /
- 近距离放射疗法 /
- 药物载体 /
- 肿瘤 /
- 剂型
Abstract: Brachytherapy using a carrier embedded with radioactive seeds has some unique advantages for the treatment of tumor bed or tumor surface, such as optimized spatial dose distribution, reduced seeds migration, expanded clinical indication and convenient treatment application. All these contribute to its better curative effect. The therapy will have a good prospect of clinical application.
- Iorlinc radioisotopes /
- Brachytherapy /
- Drug carriers /
- Ncoplasms /
- Dosage forms
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

[1]	Pisch J, Belsley SJ, Ashton R, et al. Placement of ¹²⁵Ⅰ implants with the da vinci robotic system after video-assisted thoracoscopic wedge resection:a feasibility study. Int J Radiat Oncol Biol Phys,2004, 60(3):928-932.
[2]	Voynov GH, Heron DE, Lin CJ, et al. Intraoperative I-125 vicryl mesh brachytherapy after sublobar resection for high-risk stage I non-small cell lung cancer. Int J Radiat Oncol Biol Phys, 2004, 60(1 Supple):S240-S241.
[3]	Rogers CL, Theodore DN, Dickman CA, et al. Surgery and permanent ¹²⁵Ⅰ seed paraspinal brachytherapy for malignant tumors with spinal cord compression. Int J Radiat Oncol Biol Phys, 2002,54(2):505-513.
[4]	Nanda SK, Reynolds SM, Kaiser PK, et al. Ten-year follow-up of fellow eyes of patients errolled in Collaborative Ocular Melanoma Study randomized trials:COMS report No.22. Ophthalmology,2004, 111(5):966-976.
[5]	Bashar AQ, Brendan C, Dan A, et al. The use of linked seeds eliminates lung embolization following permanent seed implantation for prostate cancer. Int J Radiat Oncol Biol Phys, 2004, 59(2):397-399.
[6]	Finger PT, Berson A, Ng T, et al. Palladium-103 plaque radiotherapy for choroidal melanoma:an 11-year study. Int J Radiat Oncol Biol Phys, 2002, 54(5):1438-1445.
[7]	Puusaari I, Heikkonen J, Summanen P, et al. Iodine brachytherapy as an alternative to enucleation for large uveal melanomas. Ophthalmology, 2003, 110(11):2223-2234.
[8]	Astrahan MA. Improved treatment planning for COMS eye plaques.Int J Radiat Oncol Biol Phys, 2005, 61(4):1227-1242.
[9]	孙平,盛祖立,张正仪,等.4种临床用烤瓷合金材料细胞毒性研究.口腔医学,2004,24(6):344-346.
[10]	Nath R, Anderson LL, Luxton G, et al. Dosimetry of interstitial brachytherapy sources:Recommendations of the AAPM Radiation Therapy Committee Task Group N0.43. Med Phys, 1995, 22(2):209-234.
[11]	Ray SK, Bhatnagar R, Hartsell WF, et al. Review of eye plaque dosimetry bawd on AAPM task group 43 recommendations. Int J Radiat Oncol Biol Phys, 1998, 41(3):701-706.
[12]	Astrahan MA. Improved treatment planning for COMS eye plaques. Int J Radiat Oncol Biol Phys, 2005, 61(4):1227-1242.
[13]	Merrick GS, Buffer WM, Dorsey AT, et al. Seed fixity in the prostate/periprostatic region following brachytherapy. Int J Radiat Oncol Biol Phys, 2000, 46(1):215-220.

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