遗传性辐射敏感综合征
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摘要: 许多遗传性疾病如唐氏综合征、共济失调性毛细血管扩张征等对辐射的损伤效应表现出高敏感性,统称为遗传性辐射敏感综合征。这些病人的体细胞辐射反应特征是染色体畸变率显着增加、细胞存活率下降、抗辐射性DNA合成,同时都具有肿瘤易感性。研究此综合征反应规律和机理对遗传病的早期诊断和基因治疗有重要意义。
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