MIBG及其衍生物的研究进展

罗全勇

MIBG及其衍生物的研究进展

罗全勇

文章导航 > 国际放射医学核医学杂志 > 2002, 26 > 5: (216-219)

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MIBG及其衍生物的研究进展

罗全勇

200233 上海, 上海市第六人民医院

作者简介: 罗全勇(1972-),男,四川隆昌人,主治医师,医学硕士,主要从事核素诊断与治疗的研究。;

中图分类号: R594.8

The recent research progress of MIBG and its derivatives

LUO Quan-yong

Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China
CLC number: R594.8

摘要: MIBG(间碘苄胍)是神经递质去甲肾上腺素的功能性类似物,其转运、潴留与释放机制均与去甲肾上腺素相似。放射性核素标记的MIBG及其衍生物既可用于嗜铬细胞瘤、神经母细胞瘤等神经嵴起源肿瘤的诊断与治疗,也可用于心肌交感神经显像,评估心肌交感神经元的完整性与功能。
- 间碘苄胍 /
- 神经内分泌肿瘤 /
- 嗜铬细胞瘤 /
- 神经母细胞瘤 /
- 心肌交感神经
Abstract: MIBG (metaiodobenzylguanidine)is a functional analog of the neurotransmitter norepinephrine.It is trans-ported,stored and rel eased by a mechanism similar to that of norepinephrine.MIBG and its derivatives are useful radio-pharmaceutical for the clinical scintigraphy and treatment of neural crest tumors such as pheochromocytoma and neurob-lastoma.Also it is applicable for myocardial imaging in evaluating the integrity and function of my ocardial presynapse sympathetic neuron.
- metaiodobenzylguanidine /
- neuroendocrine tumor /
- pheochromocytoma /
- neuroblastoma /
- myocardial sympathetic
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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