131I治疗非毒性多发结节性甲状腺肿
131I Treatment for nontoxic multinodular goiter
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摘要: 131I可以有效地减小非毒性多发结节性甲状腺肿(NTMNG)病人的甲状腺体积,减轻局部压迫症状,尤其适用于有高手术危险、术后复发及拒绝手术的患者。目前尚需更多病例及更长随访时间的研究。
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关键词:
- 非毒性多发结节性甲状腺肿 /
- 放射性碘 /
- 治疗
Abstract: 131I treatment for nontoxic multinodular goiter (NTMNG) is effective therapy to reduce the thyroid volume and to improve the local compressive symptoms, especially for the patients who are at high operative risk, have had previous thyroidectomy with goiter recurrence or refuse surgery. But a larger study and a longer follow up are required.-
Key words:
- nontoxic multinodular goiter /
- radioiodine /
- therapy
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[1] Rasmussen LB, Andersson G, Garaidsdotir J, et al.Iodine, Do we need an enrichment program in Denmark?[J]. Int J Food Sci Nutr, 1996, 47:377~381. [2] Maurer AH, Charkes ND. Radioiodine treatment for nontoxic multinodular goiter[J]. J Nucl Med, 1999, 40:1313~1316. [3] Nygaard B, Faber J, Hegedus L, et al.131I treatment of nodular non-toxic goiter[J]. Eur J Endocrinol, 1996,134:15~20. [4] Huysmans D, Hermus A, Edelbroek M et al.Radioiodine for nontoxic multinodular goiter[J].Thyroid, 1997, 7:235~239. [5] Huysmans D, Buijs W, ven Mvd, et al. Dosimetry and risk estimates of radioiodine terapy used for large,multinodular goiters[J]. J Nucl Med, 1996, 37:2072~2079. [6] Huysmans AK, Hermus RM, Edelbroek MA, et al.Autoimmune hyperthyroidism occurring late after radioiodine treatment for volume reduction of large multinodulargoiters[J]. Thyroid, 1997, 7:535~539. [7] de Klerk JM, van Isselt JW, van Dijk A et al. Iodine-131 therapy in sporadic nontoxic goiter[J]. J Nucl Med, 1997, 38:372~376.
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