中枢神经系统辐射损伤的细胞与分子机制研究进展

张燕; 陈肖华

张燕 , 陈肖华

文章导航 > 国际放射医学核医学杂志 > 2004, 28 > 1: (41-44)

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中枢神经系统辐射损伤的细胞与分子机制研究进展

张燕,
陈肖华

100850 北京, 军事医学科学院放射医学研究所
中图分类号: Q345⁺.3;R818.74

Advances in study of cellular and molecular mechanisms of radiation-induced CNS injury

Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850, China
CLC number: Q345⁺.3;R818.74

摘要: 了解中枢神经系统(central nervous system, CNS)的辐射损伤机制,对增强CNS的辐射耐受程度和治疗辐射引起的CNS损伤具有重要意义。主要从神经元、少突胶质细胞、脱髓鞘及血管系统等方面概述CNS辐射损伤的细胞机制,并简要介绍辐射诱导CNS的细胞凋亡信号转导及基因表达等分子机制。
- 辐射损伤 /
- 中枢神经系统 /
- 细胞与分子机制
Abstract: Understanding the mechanisms of radiation-induced CNS injury may help to develop strategies to increase the radiation tolerance and treat CNS injury induced by radiation.The article re-views the cellular mechanisms about neurons, oligodendrocytes, demyelination, vasculature and so on, and the molecular mechanisms of the apoptosis signal transduction and gene expression induced by radi-ation.
- radiation /
- injury central nervous system /
- cellular and molecular mechanisms
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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中枢神经系统辐射损伤的细胞与分子机制研究进展

张燕
陈肖华

100850 北京, 军事医学科学院放射医学研究所

收稿日期: 2003-06-27

关键词:

摘要: 了解中枢神经系统(central nervous system, CNS)的辐射损伤机制,对增强CNS的辐射耐受程度和治疗辐射引起的CNS损伤具有重要意义。主要从神经元、少突胶质细胞、脱髓鞘及血管系统等方面概述CNS辐射损伤的细胞机制,并简要介绍辐射诱导CNS的细胞凋亡信号转导及基因表达等分子机制。