心肌缺血性疾病基因治疗及分子影像监测进展

张国鹏; 张永学

张国鹏 , 张永学

文章导航 > 国际放射医学核医学杂志 > 2008, 32 > 5: (257-260)

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心肌缺血性疾病基因治疗及分子影像监测进展

430022 武汉, 华中科技大学同济医学院附属协和医院核医学科, 湖北省分子影像实验室
基金项目:
国家自然科学基金(30571816)

Advances in gene therapy of myocardial ischemia and the monitoring with molecular imaging

Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Scienee and Technology;Key Laboratory of Molecular Imaging, Hubei Province, Wuhan 430022, China

摘要: 心血管疾病是严重危害人类健康的疾病,目前已成为导致死亡的主要疾病之一。随着对心血管病发病的分子机制的研究进展,以及心血管病基因治疗的实验研究,基因治疗已成为心肌缺血治疗具有前景的有效方法,其中有些已经进入临床试验以验证其可行性和有效性。而如何在活体内无创性监测治疗基因的表达及其治疗效果也成为当今亟待解决的课题。
- 心肌缺血 /
- 基因疗法 /
- 分子诊断技术
Abstract: Cardiovascular diseases are harmful for people.Recent advances in understanding the molecular basis of cardiovascular diseases, together with some studies of the gene therapy on cardiovascular disorders, have offered possibilities for new treatments.Gene therapies have demonstrated potential usefulness in treating myocardial ischemia.Therefore, the monitoring of the expression of therapy gene and therapeutic efficacy has become an important issue.
- Myocardial ischemia /
- Gene therapy /
- Molecular diagnostic technigue
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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心肌缺血性疾病基因治疗及分子影像监测进展

430022 武汉, 华中科技大学同济医学院附属协和医院核医学科, 湖北省分子影像实验室

收稿日期: 2008-06-10

基金项目: 国家自然科学基金(30571816)

关键词:

摘要: 心血管疾病是严重危害人类健康的疾病,目前已成为导致死亡的主要疾病之一。随着对心血管病发病的分子机制的研究进展,以及心血管病基因治疗的实验研究,基因治疗已成为心肌缺血治疗具有前景的有效方法,其中有些已经进入临床试验以验证其可行性和有效性。而如何在活体内无创性监测治疗基因的表达及其治疗效果也成为当今亟待解决的课题。