骨髓基质细胞及其辐射残留损伤

林治栋

骨髓基质细胞及其辐射残留损伤

林治栋

文章导航 > 国际放射医学核医学杂志 > 2001, 25 > 6: (282-284)

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骨髓基质细胞及其辐射残留损伤

林治栋

300192 天津, 中国医学科学院中国协和医科大学放射医学研究所

作者简介: 林治栋(1975-),男,辽宁沈阳人,中国医学科学院、中国协和医科大学放射医学研究所硕士研究生,主要从事造血微环境研究。;

中图分类号: Q345⁺.21

Current development in the study of the bone marrow stroma cell and its radiation residual damage

LIN Zhi-dong

Institute of Radiation Medicine, China Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China
CLC number: Q345⁺.21

摘要: 骨髓微环境特别是基质细胞对骨髓的造血起着重要的调控和支持作用。基质细胞与细胞外基质协同作用,并通过分泌众多细胞因子和表达多种粘附因子形成了一个调控造血细胞增殖和分化的网络体系。基质细胞以其较大的辐射抗性对造血系统辐射残留损伤的恢复发挥重要的作用。
- 骨髓基质细胞 /
- 细胞外基质 /
- 辐射残留损伤 /
- 生长因子
Abstract: A great supportive and regulatory role has been played by the bone marrow microenvironment, esp. its component, stroma cells. Bone marrow stroma cells function cooperating with their surrounding ECM form a complicate network regulating differentiation and proliferation of hematopoietic progenitor cells.The radiation resistance exhibited by stroma cells is critical for the recovery of hematopoietic progenitor cells from residual damage.
- bone marrow stroma cell /
- microenvironment /
- residual damage /
- cytokine
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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