131I-MIBG与化疗联合治疗神经母细胞瘤的研究现状

朱瑞森

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131I-MIBG与化疗联合治疗神经母细胞瘤的研究现状

  • 中图分类号: R730.5

The study status of 131I-MIBG concomitant use with chemotherapy in the theray of neuroblastoma

  • CLC number: R730.5

  • 摘要: 神经母细胞瘤是一种侵犯儿童、恶性程度高、对射线敏感的肿瘤,近年来主要用131I-间碘苄胍(131I-MIBG)与化疗进行联合治疗,获得了良好的效果。主要综述131I-MIBG与化疗、免疫治疗等联合治疗神经母细胞瘤的几个不同方法和路径,并讨论了联合治疗的机制。
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    [6] Yanik GA, Levine JE, Matthay KK, et al. Pilot study of 131I-MIBG in combination with myelozblative chemotherapy and autologeus stem-cell support for treatment of neuroblastoma[J]. J Clin Oncol,2002, 20(8):2142-2149.
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    [9] Klingebiel T, Berthold F, Treuner J, et al. MIBG in the treatment of 47 patients with neuroblastoma:results of the German Neuroblastoma Trial[J]. Med Pediatr Oncol, 1991, 19(2):84-88.
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    [2] 邵虹 . 神经母细胞瘤的影像学诊断. 国际放射医学核医学杂志, 2002, 26(4): 148-151.
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    [5] 罗全勇 . MIBG及其衍生物的研究进展. 国际放射医学核医学杂志, 2002, 26(5): 216-219.
    [6] 袁志斌 . PET显像在内分泌肿瘤中的应用. 国际放射医学核医学杂志, 2003, 27(5): 208-211.
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    [9] 王燕唐谨 . 神经母细胞瘤的131I-MIBG显像. 国际放射医学核医学杂志, 1988, 12(1): 61-61.
    [10] 沈钰如马寄晓 . 放射性碘标记MIBG诊断儿童神经母细胞瘤的经验. 国际放射医学核医学杂志, 1991, 15(1): 49-50.
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  • 收稿日期:  2004-11-17

131I-MIBG与化疗联合治疗神经母细胞瘤的研究现状

  • 200233 上海, 上海交通大学附属第六人民医院核医学科

摘要: 神经母细胞瘤是一种侵犯儿童、恶性程度高、对射线敏感的肿瘤,近年来主要用131I-间碘苄胍(131I-MIBG)与化疗进行联合治疗,获得了良好的效果。主要综述131I-MIBG与化疗、免疫治疗等联合治疗神经母细胞瘤的几个不同方法和路径,并讨论了联合治疗的机制。

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