99mTc-葡糖二酸显像剂的研究进展

张娟 唐志刚 王学斌

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99mTc-葡糖二酸显像剂的研究进展

    通讯作者: 王学斌, xbwang@bnu.edu.cn
  • 中图分类号: R817.4

The advanced in 99mTc labeled glucaric acid

    Corresponding author: WANG Xue-bin, xbwang@bnu.edu.cn
  • CLC number: R817.4

  • 摘要: 葡糖二酸(GLA)是一种六碳二元羧酸盐的葡萄糖类似物,是葡萄糖在生物体内代谢的产物之一,存在于组织和体液中,可被99mTc标记。本文论述了GLA的制备、99mTc-GLA药盒的制备以及99mTc-GLA在心肌梗死显像和肿瘤显像中的研究进展。现有的研究结果表明,99mTc-GLA在诊断心肌梗死和某些肿瘤(如乳腺癌)表现了良好的性质,因此是一种很有应用前景和研究价值的显像剂。
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  • 收稿日期:  2005-10-18

99mTc-葡糖二酸显像剂的研究进展

    通讯作者: 王学斌, xbwang@bnu.edu.cn
  • 100875 北京, 北京师范大学化学学院教育部放射性药物重点实验室

摘要: 葡糖二酸(GLA)是一种六碳二元羧酸盐的葡萄糖类似物,是葡萄糖在生物体内代谢的产物之一,存在于组织和体液中,可被99mTc标记。本文论述了GLA的制备、99mTc-GLA药盒的制备以及99mTc-GLA在心肌梗死显像和肿瘤显像中的研究进展。现有的研究结果表明,99mTc-GLA在诊断心肌梗死和某些肿瘤(如乳腺癌)表现了良好的性质,因此是一种很有应用前景和研究价值的显像剂。

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