<sup>18</sup>F-氟代脱氧葡萄糖PET和PET-CT在转移性骨肿瘤中的应用研究

刘建军; 黄钢

¹⁸F-氟代脱氧葡萄糖PET和PET-CT在转移性骨肿瘤中的应用研究

刘建军 , 黄钢

文章导航 > 国际放射医学核医学杂志 > 2005, 29 > 5: (213-216)

引用本文:

Citation:

¹⁸F-氟代脱氧葡萄糖PET和PET-CT在转移性骨肿瘤中的应用研究

刘建军,
黄钢

200001 上海, 上海第二医科大学附属仁济医院PETCT中心
基金项目:
上海市百人计划第三轮重点资助(97BR012)

上海市教委重点发展基金(04BA03)
中图分类号: R814.42;R817.4

Application study of ¹⁸F-FDG PET and PET-CT on malignant bone metastases

PET-CT Center, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China
CLC number: R814.42;R817.4

摘要: ¹⁸F-氟代脱氧葡萄糖(¹⁸F-FDG) PET和PET-CT可直接显示转移到骨骼中的肿瘤组织,早期诊断转移性骨肿瘤,是较为敏感的一种方法。其与传统骨显像在临床应用中具有互补作用,不能相互替代,应针对不同情况具体对待。
- 转移性骨肿瘤 /
- ¹⁸F-氟代脱氧葡萄糖 /
- 正电子发射体层显像 /
- 计算机体层成像 /
- ⁹⁹Tc^m-亚甲基二膦酸盐
Abstract: ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET or PET-CT can directly detect increased glucose metabolism of neoplastic cells nested in the skeleton, making it a sensitive method for assessment of bone metastases.
- bone metastases /
- ¹⁸F-fluorodeoxyglucose /
- positron emission tomography /
- computed tomography /
- ⁹⁹Tcm-methylene diphosphonate
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

[1]	Schirrmeister H, Guhlmann A, Eisner K, et al. Sensitivity in detecting osseous lesions depends on anatomic localization:Planar bone scintigraphy versus ¹⁸F PET[J]. J Nucl Med, 1999, 40(10):1623-1629.
[2]	Hawkins RA, Choi Y, Huang SC, et al. Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET[J]. J Nucl Med, 1992,33(5):633-642.
[3]	Brenner W, Vernon C, Muzi M, et al. Comparison of different quantitative approaches to ¹⁸F-fluoride PET scans[J]. J Nucl Med, 2004, 45(9):1493-1500.
[4]	Even-Sapir E, Metser U, Flusser G, et al. Assessment of malignant skeletal disease:initial experience with ¹⁸F-fluoride PET/CT and comparison between ¹⁸F-fluoride PET and ¹⁸F-fluoride PET/CT[J]. J Nucl Med, 2004, 45(2):272-278.
[5]	Lonneux M, Borbath Ⅱ, Berliere M, et al. The place of whole-body PET FDG for the diagnosis of distant recurrence of breast cancer[J]. Clin Positron Imaging, 2000, 3(2):45-49.
[6]	Gallowitsch HJ, Kresnik E, Gasser J, et al. F-18 fluorodeoxyglucose positron-emission tomography in the diagnosis of tumor recurrence and metastases in the follow-up of patients with breast carcinoma:A comparison to conventional imaging[J]. Invest Radiol, 2003, 38(5):250-256.
[7]	Gayed I, Vu T, Johnson M, et al. Comparison of bone and 2-deoxy2-[18F]fiuoro-D-glucose positron emission tomography in the evaluation of bony metastases in lung cancer[J]. Mol Imaging Biol, 2003,5(1):26-31.
[8]	Uematsu T, Yuen S, Yukisawa S, et al. Comparison of FDG PET and SPECT for detection of bone metastases in breast cancer[J]. Am J Roentgenol, 2005, 184(4):1266-1273.
[9]	Morris MJ, Akhurst T, Osman I, et al. Fluorinated deoxyglucose positron emission tomography imaging in progressive metastatic prostate cancer[J]. Urology, 2002, 59(6):913-918.
[10]	Israel O, Militianu D, Goldberg A, et al. PET-CT assessment of bone metastases-FDG avidity and CT patterns before and after treatment[J]. J Nucl Med, 2004, 45:79P.
[11]	Metser U, Lerman H, Blank A, et al. Malignant involvement of the spine:Assessment by ¹⁸F-FDG PET-CT[J]. J Nucl Med, 2004, 45(2):279-284.

[1]	吴湖炳 . ¹⁸F-氟代脱氧葡萄糖PET-CT在头颈部肿瘤中的应用价值. 国际放射医学核医学杂志, 2005, 29(5): 205-209.
[2]	华逢春 , 管一晖 , 赵军 . ¹⁸F-氟代脱氧葡萄糖PET及PET-CT在淋巴瘤中的临床应用. 国际放射医学核医学杂志, 2005, 29(5): 216-219,226.
[3]	季仲友 . PET-CT中诊断性CT的必要性与临床应用. 国际放射医学核医学杂志, 2005, 29(5): 197-200.
[4]	蔡莉 , 李彦生 . 氟代脱氧葡萄糖与氨基酸PET在脑肿瘤中的对比研究. 国际放射医学核医学杂志, 2005, 29(1): 10-14.
[5]	袁志斌 . 正电子肿瘤阳性显像剂¹⁸F-AMT. 国际放射医学核医学杂志, 2002, 26(5): 193-195.
[6]	董孟杰 , 林祥通 , 赵军 . PET-CT在卵巢癌中的临床应用价值. 国际放射医学核医学杂志, 2005, 29(5): 209-213.
[7]	陈香 , 赵军 , 管一晖 . PET-CT常见伪影. 国际放射医学核医学杂志, 2005, 29(5): 201-205.
[8]	袁志斌 . ¹¹C-胆碱和¹⁸F-FDG在肿瘤PET中的比较. 国际放射医学核医学杂志, 2003, 27(6): 251-254.
[9]	吴华 . 骨骼和软组织肿瘤¹⁸F-FDG PET的应用进展. 国际放射医学核医学杂志, 2003, 27(2): 49-52.
[10]	尹立杰 . 双时相¹⁸F-FDG PET在肿瘤良恶性鉴别诊断中的应用. 国际放射医学核医学杂志, 2004, 28(2): 53-56.