心肌灌注显像剂:99Tcm-N-NOET

欧阳伟

心肌灌注显像剂:⁹⁹Tc^m-N-NOET

欧阳伟

文章导航 > 国际放射医学核医学杂志 > 2001, 25 > 3: (103-106)

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心肌灌注显像剂:⁹⁹Tc^m-N-NOET

欧阳伟

510282 广州, 第一军医大学珠江医院核医学科

作者简介: 欧阳伟(1963年-),男,江西务源人,第一军医大学珠江医院核医学科主治医师,讲师,医学硕士,主要从事临床核心脏病学的研究。;

中图分类号: R817.9

A myocardial perfusion imaging agent: ⁹⁹Tc^m-N-NOET

OU Yang-wei

Department of unclear medicine, Zhujiang Hospital, The First Military Medical University, Guangzhou 510282, China
CLC number: R817.9

摘要: ⁹⁹Tc^m-N-NOET{双[N-乙氧,N-乙基(二硫代氨基甲酸脂)氮化锝](V)}是一种锝标记中性亲脂性心肌灌注显像剂,具有心肌首过摄取率高、心肌滞留时间长之优点。其心肌摄取部位在细胞膜,且摄取不依赖于能量。L型钙通道阻滞剂能影响其心肌摄取。⁹⁹Tc^m-N-NOET不仅具有²⁰¹Tl类似的心肌再分布,而且其心肌灌注显像在诊断冠状动脉疾病的敏感性和特异性方面与²⁰¹Tl类似。
- ⁹⁹Tc^m-N-NOET /
- 心肌灌注显像 /
- 铊 /
- 对比研究
Abstract: Bis [N-ethoxy, N-ethyl (dithiocarbamato)] nitrido Tc (V) (⁹⁹Tc^m-^N-NOET) is a neutral lipophilic tech-netium agent of myocardial perfusion presenting the high first-pass myocardial uptake and long myocardial retention. The location of ⁹⁹Tc^m-N-NOET myocardial uptake is on cell membranes, and its myocardial uptake is not en-ergy-dependent, which is affected by L-type calcium channel inhibitor.⁹⁹Tc^m-N-NOET not only has a myocardial redistribution equivalent to ²⁰¹Tl, the sensitivity and specificity of its myocardial perfusion imaging in detecting coronary artery disease but also are similar to ²⁰¹Tl.
- technetium-99m-N-NOET /
- myocardial perfusion imaging /
- 201-thallium /
- comparative study
本作品遵循Signature-Non-Commercial Use 4.0 International (CC BY-NC 4.0)协议

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心肌灌注显像剂:⁹⁹Tc^m-N-NOET

欧阳伟

作者简介:欧阳伟(1963年-),男,江西务源人,第一军医大学珠江医院核医学科主治医师,讲师,医学硕士,主要从事临床核心脏病学的研究。

510282 广州, 第一军医大学珠江医院核医学科

收稿日期: 2000-02-07

关键词:

摘要: ⁹⁹Tc^m-N-NOET{双[N-乙氧,N-乙基(二硫代氨基甲酸脂)氮化锝](V)}是一种锝标记中性亲脂性心肌灌注显像剂,具有心肌首过摄取率高、心肌滞留时间长之优点。其心肌摄取部位在细胞膜,且摄取不依赖于能量。L型钙通道阻滞剂能影响其心肌摄取。⁹⁹Tc^m-N-NOET不仅具有²⁰¹Tl类似的心肌再分布,而且其心肌灌注显像在诊断冠状动脉疾病的敏感性和特异性方面与²⁰¹Tl类似。