Abstract: All kinds of nuclein scanning includeing SPECT、PET and PET/CT in liver carcinoma have a definite clinical impact on diagnosis,differential diagnosis between malignant and benign tumor,and evaluation of differentiation of tumor cell. Especially fluorine-18-deoxyglucose PET and carbon-11-acetate PET play a more important role in assessement of differentiation of liver carcinoma than CT and MRI. Combined with the examinations of morphology, PET/CT will provide better imaging effect for lesion' localization and characterization.