18F-氟脱氧葡萄糖符合线路诊断心肌梗死后的心肌活力
18F-fluorodeoxyglucose coincidence imaging diagnosis the myocardial viability after myocardial infarct
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摘要: 目的 利用18F-氟脱氧葡萄糖(18F-FDG)符合线路空腹/糖负荷代谢显像和99mTc-甲氧基异丁基异腈(99mTc-MIBI)来判断心肌梗死后心肌的活力。方法 24例心肌梗死患者进行血管造影、99mTc-MIBI负荷和(或)静息血流灌注检查、18F-FDG符合线路心肌代谢显像(空腹-葡萄糖负荷显像一日法)。结果 99mTc-MIBI灌注显像发现的27个缺血节段在空腹和糖负荷均有18F-FDG的摄取,心肌存活;22个缺血节段在空腹和糖负荷显像后没有18F-FDG的摄取,心肌没有活力。空腹状态心肌对18F-FDG摄取较少,有活力的心肌缺血节段显示特别清晰,图像质量较差;葡萄糖负荷后活力心肌摄取18F-FDG,图像质量有明显改善。结论 空腹和糖负荷都可判断心肌活力,空腹显像时图像的质量稍差,糖负荷能够提高图像质量。
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关键词:
- 心肌 /
- 氟脱氧葡萄糖18F /
- 99m锝甲氧基异丁基异腈 /
- 体层摄影术,发射型计算机,单光子
Abstract: Objective To evaluate the value of(18F-fluorodeoxyglucose, 18F-FDG)coincidence imaging and(99mTc-sestamibi, 99mTc-MIBI)myocardial perfusion imaging diagnosis the myocardial viability after myocardial infarct. Methods 24 cases myocardial infarcts patients undertaking angiography, 99mTc-MIBI stress and rest myocardial perfusion imaging, 18F-FDG coincidence metabolism imaging(fasting-glucose stress one day imaging) with single phone emission computer tomography. Results 27 out of 49 99mTc-MIBI reduced myocardial perfusion myocardial segments mismatch fasting and glucose stress 18F-FDG uptake suggesting the viable myocardial. 22 segments with reduced myocardial perfusion match fasting and glucose stress 18F-FDG uptake suggesting no viable myocardial. Fasting imaging viable myocardial can uptake less 18F-FDG but image well, glucose stress imaging viable myocardial can uptake more 18F-FDG and improved the image quality. Conclusions Fasting and glucose stress can show myocardial viability, imaging quality was less well in fasting and improved in glucose stress. -
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